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J-GLOBAL ID：201702239013615459   Reference number：17A1783175

Cyclic perylene diimide: Selective ligand for tetraplex DNA binding over double stranded DNA

環状ペリレンジイミド:二本鎖DNA上の四重螺旋DNA結合のための選択的配位子【Powered by NICT】

Author (7)： Vasimalla Suresh (Research Center for Biomicrosensing Technology, Kyushu Institute of Technology, Kitakyushu, Fukuoka 804-8550, Japan) ,  Sato Shinobu (Research Center for Biomicrosensing Technology, Kyushu Institute of Technology, Kitakyushu, Fukuoka 804-8550, Japan) ,  Sato Shinobu (Department of Applied Chemistry, Kyushu Institute of Technology, Kitakyushu, Fukuoka 804-8550, Japan) ,  Takenaka Fuminori (Department of Applied Chemistry, Kyushu Institute of Technology, Kitakyushu, Fukuoka 804-8550, Japan) ,  Kurose Yui (Department of Applied Chemistry, Kyushu Institute of Technology, Kitakyushu, Fukuoka 804-8550, Japan) ,  Takenaka Shigeori (Research Center for Biomicrosensing Technology, Kyushu Institute of Technology, Kitakyushu, Fukuoka 804-8550, Japan) ,  Takenaka Shigeori (Department of Applied Chemistry, Kyushu Institute of Technology, Kitakyushu, Fukuoka 804-8550, Japan)
Material： Bioorganic & Medicinal Chemistry  (Bioorganic and Medicinal Chemistry)
Volume： 25  Issue： 24  Page： 6404-6411  Publication year： Dec. 15, 2017 
JST Material Number： W0556A  ISSN： 0968-0896  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Synthesized cyclic perylene di...

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Thesaurus term： *acid imide ,  *polynuclear aromatic compound ,  *DNA ,  *quadruplex ,  telomere ,  *enzyme inhibition ,  *Telomerase ,  potassium compound ,  metal ion ,  cation ,  sodium compound ,  gene manipulation ,  antitumor drug ,  ultraviolet and visible absorption spectrum ,  circular dichroism spectrum ,  calorimetry ,  DNA topoisomerase I ,  *affinity ,  melting point ,  gel electrophoresis ,  potassium ion ,  sodium ion ,  *double strand DNA ,  *binding affinity ,  isothermal titration calorimetry ,  telomeric repeat amplification protocol
Semi thesaurus term： TA-core ,  TRAP method

Author keywords (5)： Cyclic perylene diimide ,  Tetraplex specific ligand ,  Human telomere DNA ,  Antiparallel tetraplex DNA ,  Inhibition of telomerase activity

JST classification (4)： Molecular genetics in general  (EC02010J) ,  Basic oncology in general  (GE02010R) ,  Basic research of antitumor(=antineoplastic)drugs  (GW16010A) ,  Basic research of enzyme preparations and enzyme inhibitor preparations  (GW21010W)

Substance index (1)： N,N′-[1,7-Dioxoheptane-1,7-diylbis[iminotrimethylene(piperazine-1,4-diyl)trimethylene]]perylene-3,4:9,10-bisdicarbimide

Terms in the title (6)： 環状 ,  ペリレンジイミド ,  二本鎖DNA ,  四重螺旋 ,  DNA結合 ,  配位子