Art

J-GLOBAL ID：201702240232879418   Reference number：17A0615265

Induction of antibody response in the oral cavity of dogs following intraocular (eye drop) immunization with Porphyromonas gingivalis cell lysate incorporated in pH-sensitive fusogenic polymer-modified liposomes

pH感受性膜融合性ポリマー修飾リポソームに取り込まれたPorphyromonas gingivalis細胞溶解物による眼内(点眼剤)免疫化の後のイヌ口腔の抗体産生応答の誘導

Author (6)： SHIMIZU Yosuke (Division of Veterinary Science, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Izumisano, Osaka 598-8531, Japan) ,  IWASAKI Tadashi (Division of Veterinary Science, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Izumisano, Osaka 598-8531, Japan) ,  TAJIMA Tomoko (Division of Veterinary Science, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Izumisano, Osaka 598-8531, Japan) ,  YUBA Eiji (Department of Applied Chemistry, Graduate School of Engineering, Osaka Prefecture University, Sakai, Osaka 599-8531, Japan) ,  KONO Kenji (Department of Applied Chemistry, Graduate School of Engineering, Osaka Prefecture University, Sakai, Osaka 599-8531, Japan) ,  WATARAI Shinobu (Division of Veterinary Science, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Izumisano, Osaka 598-8531, Japan)
Material： Journal of Veterinary Medical Science (Web)
Volume： 79  Issue： 2  Page： 290-298(J-STAGE)  Publication year： 2017 
JST Material Number： U1094A  ISSN： 1347-7439  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： sensitivity ,...
Semi thesaurus term： pH sensitive ,...

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Author keywords (5)： intraocular immunization ,  liposome ,  mucosal immunity ,  periodontitis ,  Porphyromonas gingivalis

JST classification (4)： Dogs,cats  (FD06010P) ,  Animal infectious diseases caused by bacteria  (FE02023A) ,  Production and application of antigens,antibodies,complements  (ED04030W) ,  Mouth(=oral cavity),esophagus  (EJ06020R)

Reference (45)：

• 1. Abiko, Y., Ogura, N., Matsuda, U., Yanagi, K. and Takiguchi, H. 1997. A human monoclonal antibody which inhibits the coaggregation activity of Porphyromonas gingivalis. Infect. Immun. 65: 3966-3969.
• 2. Baker, P. J., Evans, R. T. and Roopenian, D. C. 1994. Oral infection with Porphyromonas gingivalis and induced alveolar bone loss in immunocompetent and severe combined immunodeficient mice. Arch. Oral Biol. 39: 1035-1040.
• 3. Beachey, E. H. 1981. Bacterial adherence: adhesin-receptor interactions mediating the attachment of bacteria to mucosal surface. J. Infect. Dis. 143: 325-345.
• 4. Bouvet, J. P. and Fischetti, V. A. 1999. Diversity of antibody-mediated immunity at the mucosal barrier. Infect. Immun. 67: 2687-2691.
• 5. Bülow, R. and Boothroyd, J. C. 1991. Protection of mice from fatal Toxoplasma gondii infection by immunization with p30 antigen in liposomes. J. Immunol. 147: 3496-3500.

Terms in the title (14)： pH感受性 ,  膜融合 ,  ポリマー ,  修飾 ,  リポソーム ,  Porphyromonas ,  細胞溶解 ,  眼 ,  点眼剤 ,  免疫化 ,  イヌ ,  口腔 ,  抗体産生応答 ,  誘導