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J-GLOBAL ID：201702241386108405   Reference number：17A1098707

The effect of CYP3A5 genetic polymorphisms on adverse events in patients with ulcerative colitis treated with tacrolimus

タクロリムスで治療した潰瘍性大腸炎患者における有害事象に対するCYP3A5の遺伝的多型の影響【Powered by NICT】

Author (10)： Asada Ayumi (Department of Medicine, Shiga University of Medical Science, Otsu, Japan) ,  Bamba Shigeki (Department of Medicine, Shiga University of Medical Science, Otsu, Japan) ,  Morita Yukihiro (Department of Medicine, Shiga University of Medical Science, Otsu, Japan) ,  Takahashi Kenichiro (Department of Medicine, Shiga University of Medical Science, Otsu, Japan) ,  Imaeda Hirotsugu (Department of Medicine, Shiga University of Medical Science, Otsu, Japan) ,  Nishida Atsushi (Department of Medicine, Shiga University of Medical Science, Otsu, Japan) ,  Inatomi Osamu (Department of Medicine, Shiga University of Medical Science, Otsu, Japan) ,  Sugimoto Mitsushige (Department of Medicine, Shiga University of Medical Science, Otsu, Japan) ,  Sasaki Masaya (Department of Medicine, Shiga University of Medical Science, Otsu, Japan) ,  Andoh Akira (Department of Medicine, Shiga University of Medical Science, Otsu, Japan)
Material： Digestive and Liver Disease
Volume： 49  Issue： 1  Page： 24-28  Publication year： 2017 
JST Material Number： W3234A  ISSN： 1590-8658  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Tacrolimus is an immunosuppres...

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Thesaurus term： Genotype ,  chi-square test ,  oral administration ,  *ulcerative colitis ,  *genetic polymorphism ,  renal toxicity ,  pharmacokinetics ,  *patient ,  immunosuppressant ,  induction chemotherapy ,  *adverse reaction ,  *Inflammation ,  *ulcer ,  *symptom ,  *colitis (large intestine) ,  *Enteritis ,  ether ,  ketone ,  macrocyclic compound ,  nitrogen heterocyclic compound ,  oxygen heterocyclic compound ,  bridged compound ,  allyl compound ,  alicyclic alcohol
Semi thesaurus term： 発生率 ,  転帰 ,  *有害事象 , 【Automatic Indexing@JST】

Author keywords (3)： Adverse events ,  Nephrotoxicity ,  Single nucleotide polymorphism

JST classification (3)： Digestive system diseases  (GH03000W) ,  Clinical biopharmacy  (GY01022L) ,  Treatment for digestive system diseases in general  (GH05010V)

Substance index (1)： Tacrolimus

Terms in the title (7)： タクロリムス ,  治療 ,  潰瘍性大腸炎 ,  患者 ,  有害事象 ,  CYP3A5 ,  遺伝的多型