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J-GLOBAL ID：201702241622651914   Reference number：17A0681524

Ventricular Tachycardia as a Complication of Ledipasvir and Sofosbuvir Treatment for HCV Infection

HCV感染症へのレジパスビルおよびソホスブビル治療の合併症としての心室性頻拍

Author (7)： Nirei Kazushige (Division of Gastroenterology and Hepatology, Department of Internal Medicine, Nihon University School of Medicine, Japan) ,  Nakamura Hitomi (Division of Gastroenterology and Hepatology, Department of Internal Medicine, Nihon University School of Medicine, Japan) ,  Matsuoka Shunichi (Division of Gastroenterology and Hepatology, Department of Internal Medicine, Nihon University School of Medicine, Japan) ,  Yamana Yoichiro (Division of Gastroenterology and Hepatology, Department of Internal Medicine, Nihon University School of Medicine, Japan) ,  Yoda Shunichi (Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Japan) ,  Hirayama Atsushi (Division of Cardiology, Department of Medicine, Nihon University School of Medicine, Japan) ,  Moriyama Mitsuhiko (Division of Gastroenterology and Hepatology, Department of Internal Medicine, Nihon University School of Medicine, Japan)
Material： Internal Medicine (Web)  (Intern Med (Web))
Volume： 56  Issue： 7  Page： 787-790(J-STAGE)  Publication year： 2017 
JST Material Number： U0033A  ISSN： 1349-7235  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human(primates) ,...

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Author keywords (3)： chronic hepatitis C ,  ledipasvir and sofosbuvir ,  ventricular tachycardia

JST classification (1)： Cardiovascular system diseases  (GJ03000C)

Substance index (2)： Sofosbuvir ,  Ledipasvir

Reference (16)：

• 1. Katayama K, Tanaka J, Komiya Y, Kumagai J, Yoshizawa H. Significance of medical examination for HCV infection as a national project for prevention of hepatocellular carcinoma in Japan. Nihon Rinsho 62: 248-252, 2004.
• 2. Afdhal N, Zeuzem S, Kwo P, et al.; ION-1 Investigators. Ledipasvir and sofosbuvir for untreated HCV genotype 1 infection. N Engl J Med 15: 1889-1898, 2014 (in Japanese).
• 3. Afdhal N, Reddy KR, Nelson DR, et al.; ION-2 Investigators. Ledipasvir and sofosbuvir for previously treated HCV genotype 1 infection. N Engl J Med 17: 1483-1493, 2014.
• 4. Kowdley KV, Gordon SC, Reddy KR, et al.; ION-3 Investigators. Ledipasvir and sofosbuvir for 8 or 12 weeks for chronic HCV without cirrhosis. N Engl J Med 15: 1879-1888, 2014.
• 5. Renet S, Chaumais MC, Antonini T, et al. Extreme bradycardia after first doses of sofosbuvir and daclatasvir in patients receiving amiodarone: 2 cases including a rechallenge. Gastroenterology 149: 1378-1380.e1, 2015.

Terms in the title (6)： HCV感染症 ,  レジパスビル ,  ソホスブビル ,  治療 ,  合併症 ,  心室性頻拍