Art

J-GLOBAL ID：201702242814758712   Reference number：17A1534134

Actions of Propofol on Neurons in the Cerebral Cortex

大脳皮質中のニューロンへのプロポフォールの作用

Author (5)： Kobayashi Masayuki (Department of Pharmacology, Nihon University School of Dentistry) ,  Kobayashi Masayuki (Division of Oral and Craniomaxillofacial Research, Dental Research Center, Nihon University School of Dentistry) ,  Kobayashi Masayuki (RIKEN Center for Life Science Technologies) ,  Oi Yoshiyuki (Department of Anesthesiology, Nihon University School of Dentistry) ,  Oi Yoshiyuki (Division of Immunology and Pathobiology, Dental Research Center, Nihon University School of Dentistry)
Material： Journal of Nippon Medical School  (日本医科大学雑誌)
Volume： 84  Issue： 4  Page： 165-169(J-STAGE)  Publication year： 2017 
JST Material Number： F0887A  ISSN： 1345-4676  CODEN： JNMSF5  Document type： Article
Article type： 文献レビュー  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： cerebral cortex ,...
Semi thesaurus term： *cellular signal transduction

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Author keywords (4)： neocortex ,  synaptic transmission ,  ion current ,  anesthetics

JST classification (1)： Basic research of general anesthetics  (GW03020L)

Substance index (1)： Propofol

Reference (45)：

• 1. Alkire MT, Hudetz AG, Tononi G: Consciousness and anesthesia. Science 2008; 322: 876-880.
• 2. Bacci A, Rudolph U, Huguenard JR, Prince DA: Major differences in inhibitory synaptic transmission onto two neocortical interneuron subclasses. J Neurosci 2003; 23: 9664-9674.
• 3. Bieda MC, MacIver MB: Major role for tonic GABA_A conductances in anesthetic suppression of intrinsic neuronal excitability. J Neurophysiol 2004; 92: 1658-1667.
• 4. Buggy DJ, Nicol B, Rowbotham DJ, Lambert DG: Effects of intravenous anesthetic agents on glutamate release: a role for GABA_A receptor-mediated inhibition. Anesthesiology 2000; 92: 1067-1073.
• 5. Carlson SL, Bohnsack JP, Patel V, Morrow AL: Regulation of extrasynaptic GABA_A α4 receptors by ethanol-induced protein kinase A, but not protein kinase C activation in cultured rat cerebral cortical neurons. J Pharmacol Exp Ther 2016; 356: 148-156.

Terms in the title (3)： 大脳皮質 ,  ニューロン ,  プロポフォール