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J-GLOBAL ID：201702243673459535   Reference number：17A1493038

Comparison of Clinically Relevant Mutation Profiles Between Preoperative Biopsy and Corresponding Surgically Resected Specimens in Japanese Patients With Non-Small-cell Lung Cancer by Amplicon-based Massively Parallel Sequencing

アンプリコンベース超並列シーケンシングによる非小細胞肺癌の日本人患者における術前生検と対応する外科的に切除した標本の臨床的に意義のある変異プロファイルの比較【Powered by NICT】

Author (20)： Isaka Mitsuhiro (Division of Thoracic Surgery, Shizuoka Cancer Center, Nagaizumi-cho, Sunto-gun, Japan) ,  Serizawa Masakuni (Drug Discovery and Development Division, Research Institute, Shizuoka Cancer Center, Nagaizumi-cho, Sunto-gun, Japan) ,  Kenmotsu Hirotsugu (Division of Thoracic Oncology, Shizuoka Cancer Center, Nagaizumi-cho, Sunto-gun, Japan) ,  Koh Yasuhiro (Drug Discovery and Development Division, Research Institute, Shizuoka Cancer Center, Nagaizumi-cho, Sunto-gun, Japan) ,  Koh Yasuhiro (Third Department of Internal Medicine, Wakayama Medical University, Kimiidera, Wakayama, Japan) ,  Takahashi Shoji (Division of Thoracic Surgery, Shizuoka Cancer Center, Nagaizumi-cho, Sunto-gun, Japan) ,  Maniwa Tomohiro (Division of Thoracic Surgery, Shizuoka Cancer Center, Nagaizumi-cho, Sunto-gun, Japan) ,  Wakuda Kazushige (Division of Thoracic Oncology, Shizuoka Cancer Center, Nagaizumi-cho, Sunto-gun, Japan) ,  Ono Akira (Division of Thoracic Oncology, Shizuoka Cancer Center, Nagaizumi-cho, Sunto-gun, Japan) ,  Naito Tateaki (Division of Thoracic Oncology, Shizuoka Cancer Center, Nagaizumi-cho, Sunto-gun, Japan) ,  Murakami Haruyasu (Division of Thoracic Oncology, Shizuoka Cancer Center, Nagaizumi-cho, Sunto-gun, Japan) ,  Mori Keita (Clinical Trial Coordination Office, Shizuoka Cancer Center, Nagaizumi-cho, Sunto-gun, Japan) ,  Endo Masahiro (Division of Diagnostic Radiology, Shizuoka Cancer Center, Nagaizumi-cho, Sunto-gun, Japan) ,  Abe Masato (Division of Pathology, Shizuoka Cancer Center, Nagaizumi-cho, Sunto-gun, Japan) ,  Hayashi Isamu (Division of Pathology, Shizuoka Cancer Center, Nagaizumi-cho, Sunto-gun, Japan) ,  Nakajima Takashi (Division of Pathology, Shizuoka Cancer Center, Nagaizumi-cho, Sunto-gun, Japan) ,  Yamamoto Nobuyuki (Division of Thoracic Oncology, Shizuoka Cancer Center, Nagaizumi-cho, Sunto-gun, Japan) ,  Yamamoto Nobuyuki (Third Department of Internal Medicine, Wakayama Medical University, Kimiidera, Wakayama, Japan) ,  Takahashi Toshiaki (Division of Thoracic Oncology, Shizuoka Cancer Center, Nagaizumi-cho, Sunto-gun, Japan) ,  Ohde Yasuhisa (Division of Thoracic Surgery, Shizuoka Cancer Center, Nagaizumi-cho, Sunto-gun, Japan)
Material： Clinical Lung Cancer
Volume： 18  Issue： 5  Page： 519-526.e1  Publication year： 2017 
JST Material Number： W3210A  ISSN： 1525-7304  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Amplicon-based massively paral...

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Thesaurus term： *patient ,  DNA ,  *Surgery ,  *lung tumor ,  tumor ,  Mutation ,  *Biopsy ,  excision ,  *non-small cell lung cancer ,  gene frequency ,  gene ,  *amplicon ,  bronchoscopic biopsy ,  *Japanese ,  *Genetic Variation ,  *clinical laboratory test ,  Heredity ,  population genetics
Semi thesaurus term： *variation(biology) , 【Automatic Indexing@JST】

Author keywords (5)： Amplicon-based massively parallel sequencing ,  Genetic alterations ,  NSCLC ,  Surgical specimens ,  Transbronchial biopsy specimens

JST classification (1)： Tumors(=neoplasms)of respiratory system  (GI04000G)

Terms in the title (12)： アンプリコン ,  超並列 ,  非小細胞肺癌 ,  日本人 ,  患者 ,  術前 ,  生検 ,  外科 ,  標本 ,  臨床 ,  変異 ,  プロファイル