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J-GLOBAL ID：201702244630343828   Reference number：17A0408876

Theobromine up-regulates cerebral brain-derived neurotrophic factor and facilitates motor learning in mice

テオブロミンは脳脳由来神経栄養因子を上方制御し,マウスの運動学習を促進する【Powered by NICT】

Author (11)： Yoneda Mitsugu (Impairment Study, Graduate School of Medical Sciences, Kanazawa University, 5-11-80 Kodatsuno, Takara-machi, Kanazawa, 920-0942, Japan) ,  Sugimoto Naotoshi (Department of Physiology, Graduate School of Medical Sciences, Kanazawa University, 13-1 Takara-machi, Kanazawa, 920-8640, Japan) ,  Sugimoto Naotoshi (Pediatrics, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, 920-8640, Japan) ,  Sugimoto Naotoshi (Department of Environmental Physiology, School of Medicine, Shimane University, 89-1 Enya-machi, Izumo, 693-8501, Japan) ,  Katakura Masanori (Department of Environmental Physiology, School of Medicine, Shimane University, 89-1 Enya-machi, Izumo, 693-8501, Japan) ,  Katakura Masanori (Department of Nutritional Physiology, Faculty of Pharmaceutical Sciences, Josai University, 1-1 Keyakidai, Sakado, 350-0295, Japan) ,  Matsuzaki Kentaro (Department of Environmental Physiology, School of Medicine, Shimane University, 89-1 Enya-machi, Izumo, 693-8501, Japan) ,  Tanigami Hayate (Impairment Study, Graduate School of Medical Sciences, Kanazawa University, 5-11-80 Kodatsuno, Takara-machi, Kanazawa, 920-0942, Japan) ,  Yachie Akihiro (Pediatrics, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, 920-8640, Japan) ,  Ohno-Shosaku Takako (Impairment Study, Graduate School of Medical Sciences, Kanazawa University, 5-11-80 Kodatsuno, Takara-machi, Kanazawa, 920-0942, Japan) ,  Shido Osamu (Department of Environmental Physiology, School of Medicine, Shimane University, 89-1 Enya-machi, Izumo, 693-8501, Japan)
Material： Journal of Nutritional Biochemistry  (JNB)
Volume： 39  Page： 110-116  Publication year： 2017 
JST Material Number： E0597B  ISSN： 0955-2863  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： Theobromine, which is a caffei...

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Thesaurus term： phosphodiesterase ,  *BDNF ,  phosphoprotein ,  oral administration ,  *up-regulation ,  phosphoric acid ,  phosphorylation ,  CRE binding protein ,  adenine nucleotide ,  ribonucleotide ,  cyclic nucleotide ,  lactam ,  central nervous system stimulant ,  urea compound
Semi thesaurus term： VASP ,  細胞生存 ,  結合蛋白質 ,  阻害剤 , 【Automatic Indexing@JST】

Author keywords (6)： cAMP ,  Phosphodiesterase ,  Motor learning ,  VASP phosphorylation ,  BDNF ,  CREB phosphorylation

JST classification (6)： Edible fats and oils,margarines  (FJ09010C) ,  Metabolism and nutrition of lipids  (EJ02034Q) ,  Food chemistry,nutritional value  (FJ01020J) ,  Cell physiology in general  (EF02010S) ,  Basic neurology  (GN01020W) ,  Basic medicine on cardiovascular system  (GJ01020K)

Substance index (3)： cAMP ,  Caffeine ,  Theobromine

Terms in the title (7)： テオブロミン ,  脳 ,  脳由来神経栄養因子 ,  上方制御 ,  マウス ,  運動学習 ,  促進