Art

J-GLOBAL ID：201702245456381250   Reference number：17A0304367

Genetic and clinical characteristics of Japanese patients with sporadic somatotropinoma

散発性成長ホルモン分泌腺腫の日本人患者の遺伝的および臨床特性

Author (14)： Matsumoto Ryusaku (Division of Diabetes and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan) ,  Izawa Masako (Department of Pediatric Endocrinology and Metabolism, Aichi Children’s Health and Medical Center, Obu, Japan) ,  Fukuoka Hidenori (Division of Diabetes and Endocrinology, Kobe University Hospital, Kobe, Japan) ,  Iguchi Genzo (Division of Diabetes and Endocrinology, Kobe University Hospital, Kobe, Japan) ,  Odake Yukiko (Division of Diabetes and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan) ,  Yoshida Kenichi (Division of Diabetes and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan) ,  Bando Hironori (Division of Diabetes and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan) ,  Suda Kentaro (Division of Diabetes and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan) ,  Nishizawa Hitoshi (Division of Diabetes and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan) ,  Takahashi Michiko (Division of Diabetes and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan) ,  Inoshita Naoko (Department of Pathology, Toranomon Hospital, Tokyo, Japan) ,  Yamada Shozo (Department of Hypothalamic and Pituitary Surgery, Toranomon Hospital, Tokyo, Japan) ,  Ogawa Wataru (Division of Diabetes and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan) ,  Takahashi Yutaka (Division of Diabetes and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan)
Material： Endocrine Journal  (Endocr J)
Volume： 63  Issue： 11  Page： 953-963(J-STAGE)  Publication year： 2016 
JST Material Number： F0625A  ISSN： 0918-8959  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human ,...
Semi thesaurus term： *Growth hormone secreting adenoma

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Author keywords (5)： Acromegaly ,  Gigantism ,  GNAS ,  AIP ,  GPR101

JST classification (2)： Tumors(=neoplasms)of endocrine system  (GL04000P) ,  Clinical oncology in general  (GE03010Y)

Reference (28)：

• 1. Melmed S (2006) Acromegaly. N Engl J Med 355: 2558-2573.
• 2. Dekkers OM, Biermasz NR, Pereira AM, Romijn JA, Vandenbroucke JP (2008) Mortality in Acromegaly: A Metaanalysis. J Clin Endocrinol Metab 93: 61-67.
• 3. Rowles SV, Prieto L, Badia X, Shalet SM, Webb SM, et al. (2005) Quality of life (QOL) in patients with acromegaly is severely impaired: use of a novel measure of QOL: acromegaly quality of life questionnaire. J Clin Endocrinol Metab 90: 3337-3341.
• 4. Melmed S (2009) Acromegaly pathogenesis and treatment. J Clin Invest 119: 3189-3202.
• 5. Landis CA, Masters SB, Spada A, Pace AM, Bourne HR, et al. (1989) GTPase inhibiting mutations activate the [alpha] chain of Gs and stimulate adenylyl cyclase in human pituitary tumours. Nature 340: 692-696.

Terms in the title (5)： 成長ホルモン分泌腺腫 ,  日本人 ,  患者 ,  遺伝 ,  臨床