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J-GLOBAL ID：201702250019008322   Reference number：17A1688653

Andrographolide from the herb Andrographis paniculata induces apoptosis on cultured human leukemic cells

ハーブAndrographis paniculataから抽出したアンドログラフォライドはヒト培養白血病細胞においてアポトーシスを誘発する

Author (6)： Doi Hiroki (Faculty of Medical Technology, Master Course in Fujita Health University Graduate School of Health Sciences) ,  Matsui Taei (Faculty of Medical Technology, Master Course in Fujita Health University Graduate School of Health Sciences) ,  Ohye Tamae (Faculty of Medical Technology, Master Course in Fujita Health University Graduate School of Health Sciences) ,  Saito Kuniaki (Faculty of Medical Technology, Master Course in Fujita Health University Graduate School of Health Sciences) ,  Katsuda Itsuro (Department of Internal Medicine, Fujita Health University, School of Medicine) ,  Akiyama Hidehiko (Faculty of Medical Technology, Master Course in Fujita Health University Graduate School of Health Sciences)
Material： Fujita Medical Journal (Web)  (Fujita Med J (Web))
Volume： 3  Issue： 3  Page： 48-54(J-STAGE)  Publication year： 2017 
JST Material Number： U0775A  ISSN： 2189-7255  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human(primates) ,...
Semi thesaurus term： Andrographis paniculata ,...

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Author keywords (4)： Andrographis paniculata ,  Andrographolide ,  Apoptosis ,  Leukemic cells

JST classification (1)： Basic research of antitumor(=antineoplastic)drugs  (GW16010A)

Substance index (1)： Andrographolide

Reference (25)：

• 1. Varma A, Padh H, Shrivastava N. Andrographolide: a new plant-derived antineoplastic entity on horizon. Evid Based Complement Alternat Med 2011; 10: 1-9.
• 2. Cragg GM, Newman DJ. Plants as a source of anti-cancer agents. J Ethnopharmacol 2005; 100: 72-79.
• 3. Palem PP, Kuriakose GC, Jayabaskaran C. An endophytic fungus, talaromyces radicus, isolated from catharanthus roseus, produces vincristine and vinblastine, which induce apoptotic cell death. PLoS One 2015; 11: 1-22.
• 4. Rajabalian S. Methanolic extract of Teucrium polium L. potentiates the cytotoxic and apoptotic effects of anticancer drugs of vincristine, vinblastine and doxorubicin against a panel of cancerous cell lines. Exp Oncol 2008; 30: 133-138.
• 5. Hossain MS, Urbi Z, Sule A, Hafizur Rahman KM. Andrographis paniculata (Burm. f.) Wall. ex Nees: a review of ethnobotany, phytochemistry, and pharmacology. Scientific World Journal 2014; 24: 1-50.

Terms in the title (7)： ハーブ ,  Andrographis ,  ヒト ,  培養 ,  白血病細胞 ,  アポトーシス ,  誘発