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J-GLOBAL ID：201702250201027902   Reference number：17A1434637

Functional characterization of the neuron-restrictive silencer element in the human tryptophan hydroxylase 2 gene expression

ヒトトリプトファンヒドロキシラーゼ2遺伝子発現のニューロン特異的サイレンサー要素の機能的特性化【Powered by NICT】

Author (10)： Nawa Yukino (Institute of Radioisotope Research, St. Marianna University Graduate School of Medicine, Kawasaki, Japan) ,  Kaneko Hanae (Institute of Radioisotope Research, St. Marianna University Graduate School of Medicine, Kawasaki, Japan) ,  Oda Masayuki (Department of Pharmacogenomics, St. Marianna University Graduate School of Medicine, Kawasaki, Japan) ,  Tsubonoya Masaaki (Institute of Radioisotope Research, St. Marianna University Graduate School of Medicine, Kawasaki, Japan) ,  Hiroi Tomoko (Institute of Radioisotope Research, St. Marianna University Graduate School of Medicine, Kawasaki, Japan) ,  Gentile Maria Teresa (Laboratory of Molecular and Cellular Pathology, Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, Second University of Naples, Caserta, Italy) ,  Colucci-D'Amato Luca (Laboratory of Molecular and Cellular Pathology, Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, Second University of Naples, Caserta, Italy) ,  Takahashi Ryoya (Department of Biochemistry, Faculty of Pharmaceutical Sciences, Toho University, Funabashi, Japan) ,  Matsui Hiroaki (Institute of Radioisotope Research, St. Marianna University Graduate School of Medicine, Kawasaki, Japan) ,  Matsui Hiroaki (Department of Molecular and Behavioral Neuroscience, St. Marianna University Graduate School of Medicine, Kawasaki, Japan)
Material： Journal of Neurochemistry  (J Neurochem)
Volume： 142  Issue： 6  Page： 827-840  Publication year： 2017 
JST Material Number： B0504B  ISSN： 0022-3042  CODEN： JONRA  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： Tryptophan hydroxylase 2 (TPH2...

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Thesaurus term： histone deacetylase ,  *tryptophan hydroxylase ,  *neuron ,  *human(primates) ,  fusion protein ,  electrophoresis ,  *gene expression ,  promoter(genetics) ,  enzyme inhibitor ,  nitrogen heterocyclic compound ,  phenolic compound ,  polynuclear aromatic compound ,  primary amine
Semi thesaurus term： 転写調節 ,  阻害剤 ,  DNA結合 ,  プロモーター活性 ,  REST , 【Automatic Indexing@JST】

Author keywords (6)： gene expression ,  NRSF ,  promoter ,  serotonergic neuron ,  TPH2 ,  transcriptional regulation

JST classification (2)： Enzyme in general  (EB09010D) ,  Gene expression  (EC02040Q)

Substance index (1)： Serotonin

Terms in the title (7)： ヒト ,  トリプトファンヒドロキシラーゼ2 ,  遺伝子発現 ,  ニューロン ,  サイレンサー ,  要素 ,  特性化