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J-GLOBAL ID：201702253193550093   Reference number：17A0506655

Characteristics of Japanese aldosterone-producing adenomas with KCNJ5 mutations

KCNJ5突然変異を持つ日本人のアルドステロン産生性腺腫の特徴

Author (19)： Okamura Takashi (Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan) ,  Nakajima Yasuyo (Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan) ,  Katano-Toki Akiko (Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan) ,  Horiguchi Kazuhiko (Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan) ,  Matsumoto Shunichi (Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan) ,  Yoshino Satoshi (Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan) ,  Yamada Eijiro (Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan) ,  Tomaru Takuya (Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan) ,  Ishii Sumiyasu (Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan) ,  Saito Tsugumichi (Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan) ,  Ozawa Atsushi (Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan) ,  Shibusawa Nobuyuki (Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan) ,  Satoh Tetsurou (Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan) ,  Okada Shuichi (Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan) ,  Nagaoka Rin (Department of Thoracic and Visceral Organ Surgery, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan) ,  Takada Daisuke (Department of Thoracic and Visceral Organ Surgery, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan) ,  Horiguchi Jun (Department of Thoracic and Visceral Organ Surgery, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan) ,  Oyama Tetsunari (Department of Diagnostic Pathology, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan) ,  Yamada Masanobu (Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan)
Material： Endocrine Journal  (Endocr J)
Volume： 64  Issue： 1  Page： 39-47(J-STAGE)  Publication year： 2017 
JST Material Number： F0625A  ISSN： 0918-8959  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human(primates) ,...
Semi thesaurus term： KCNJ5 gene ,...

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Author keywords (4)： KCNJ5 ,  APAs ,  Adrenocortical adenomas ,  Steroidogenic enzymes

JST classification (2)： Tumors(=neoplasms)of endocrine system  (GL04000P) ,  Clinical oncology in general  (GE03010Y)

Substance index (1)： Aldosterone

Reference (38)：

• 1. Funder JW, Carey RM, Fardella C, Gomez-Sanchez CE, Mantero F, et al. (2008) Case detection, diagnosis, and treatment of patients with primary aldosteronism: an endocrine society clinical practice guideline. J Clin Endocrinol Metab 93: 3266-3281.
• 2. Douma S, Petidis K, Doumas M, Papaefthimiou P, Triantafyllou A, et al. (2008) Prevalence of primary hyperaldosteronism in resistant hypertension: a retrospective observational study. Lancet 371: 1921-1926.
• 3. Mulatero P, Stowasser M, Loh KC, Fardella CE, Gordon RD, et al. (2004) Increased diagnosis of primary aldosteronism, including surgically correctable forms, in centers from five continents. J Clin Endocrinol Metab 89: 1045-1050.
• 4. Rossi GP, Seccia TM, Pessina AC (2008) Primary aldosteronism - part I: prevalence, screening, and selection of cases for adrenal vein sampling. J Nephrol 21: 447-454.
• 5. Young WF (2007) Primary aldosteronism: renaissance of a syndrome. Clin Endocrinol (Oxf) 66: 607-618.

Terms in the title (4)： 突然変異 ,  日本人 ,  アルドステロン ,  腺腫