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J-GLOBAL ID：201702254928656863   Reference number：17A2007800

Impediment of Replication Forks by Long Non-coding RNA Provokes Chromosomal Rearrangements by Error-Prone Restart

長鎖非コードRNAによる複製フォークの障害は誤りがちな再起動による染色体再配列を誘発する【Powered by NICT】

Author (15)： Watanabe Takaaki (Cedars-Sinai Medical Center, West Hollywood, CA 90048, USA) ,  Watanabe Takaaki (Department of Molecular Genetics, Cleveland Clinic Lerner Research Institute, Cleveland, OH 44195, USA) ,  Marotta Michael (Department of Molecular Genetics, Cleveland Clinic Lerner Research Institute, Cleveland, OH 44195, USA) ,  Suzuki Ryusuke (Cedars-Sinai Medical Center, West Hollywood, CA 90048, USA) ,  Diede Scott J. (Division of Clinical Research and Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA) ,  Tapscott Stephen J. (Division of Clinical Research and Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA) ,  Niida Atsushi (Division of Health Medical Computational Science, Health Intelligence Center, Institute of Medical Science, University of Tokyo, Tokyo 108-8639, Japan) ,  Chen Xiongfong (Advanced Biomedical Computing Center, Leidos Biomedical Research, Inc., National Cancer Institute at Frederick, Frederick, MD 21701, USA) ,  Mouakkad Lila (Cedars-Sinai Medical Center, West Hollywood, CA 90048, USA) ,  Kondratova Anna (Department of Molecular Genetics, Cleveland Clinic Lerner Research Institute, Cleveland, OH 44195, USA) ,  Giuliano Armando E. (Cedars-Sinai Medical Center, West Hollywood, CA 90048, USA) ,  Orsulic Sandra (Cedars-Sinai Medical Center, West Hollywood, CA 90048, USA) ,  Tanaka Hisashi (Cedars-Sinai Medical Center, West Hollywood, CA 90048, USA) ,  Tanaka Hisashi (Department of Molecular Genetics, Cleveland Clinic Lerner Research Institute, Cleveland, OH 44195, USA) ,  Tanaka Hisashi (Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH 44195, USA)
Material： Cell Reports
Volume： 21  Issue： 8  Page： 2223-2235  Publication year： 2017 
JST Material Number： W3124A  ISSN： 2211-1247  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Naturally stalled replication ...

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Thesaurus term： *duplicate ,  genome ,  Chromosome Aberrations ,  tumor cell ,  *chromosome ,  tumorigenesis ,  DNA lesion ,  molecular pathways ,  Gene Knockdown Technique ,  DNA polymerase eta ,  BRCA2 Protein ,  minichromosome ,  *Chromosomal rearrangements ,  *replicating fork ,  *Long Untranslated RNA ,  cellular genetic phenomenon

Author keywords (5)： stalled replication forks ,  gross chromosomal rearrangements ,  double-minute chromosomes ,  DNA damage tolerance ,  replication-transcription conflicts

JST classification (3)： Molecular genetics in general  (EC02010J) ,  Gene replication  (EC02030F) ,  Enzyme in general  (EB09010D)

Terms in the title (7)： 長鎖非コードRNA ,  複製フォーク ,  障害 ,  誤り ,  再起動 ,  染色体再配列 ,  誘発