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J-GLOBAL ID：201702255404021225   Reference number：17A0578802

Knock-in strategy at 3′-end of Crx gene by CRISPR/Cas9 system shows the gene expression profiles during human photoreceptor differentiation

CRISPR / Cas9システムによるCrx遺伝子の3 ́末端におけるノックイン戦略は,ヒト光受容体分化における遺伝子発現プロファイルを示す

Author (3)： Homma Kohei (Department of Physiology, Nippon Medical School, 1-25-16 Nezu, Bunkyo-ku, Tokyo, 113-0031, Japan) ,  Usui Sumiko (Department of Physiology, Nippon Medical School, 1-25-16 Nezu, Bunkyo-ku, Tokyo, 113-0031, Japan) ,  Kaneda Makoto (Department of Physiology, Nippon Medical School, 1-25-16 Nezu, Bunkyo-ku, Tokyo, 113-0031, Japan)
Material： Genes to Cells  (Genes Cells)
Volume： 22  Issue： 3  Page： 250-264  Publication year： Mar. 2017 
JST Material Number： W0935A  ISSN： 1356-9597  CODEN： GECEFL  Document type： Article
Article type： 原著論文  Country of issue： Australia (AUS)  Language： ENGLISH (EN)

Thesaurus term： gene expression ,...
Semi thesaurus term： genetic regulation ,...

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JST classification (2)： Gene manipulation  (EC02050B) ,  Cell physiology in general  (EF02010S)

Reference (81)：

• Akimoto, M., Cheng, H., Zhu, D., Brzezinski, J.A., Khanna, R., Filippova, E., Oh, E.C., Jing, Y., Linares, J.L., Brooks, M., Zareparsi, S., Mears, A.J., Hero, A., Glaser, T. & Swaroop, A. (2006) Targeting of GFP to newborn rods by Nrl promoter and temporal expression profiling of flow-sorted photoreceptors. Proc. Natl Acad. Sci. USA 103, 3890-3895.
• Baek, J.H., Hatakeyama, J., Sakamoto, S., Ohtsuka, T. & Kageyama, R. (2006) Persistent and high levels of Hes1 expression regulate boundary formation in the developing central nervous system. Development 133, 2467-2476.
• Balenci, L. & van der Kooy, D. (2014) Notch signaling induces retinal stem-like properties in perinatal neural retina progenitors and promotes symmetric divisions in adult retinal stem cells. Stem Cells Dev. 23, 230-244.
• Barrow, A.J. & Wu, S.M. (2009) Low-conductance HCN1 ion channels augment the frequency response of rod and cone photoreceptors. J. Neurosci. 29, 5841-5853.
• Boucherie, C., Mukherjee, S., Henckaerts, E., Thrasher, A.J., Sowden, J.C. & Ali, R.R. (2013) Brief report: self-organizing neuroepithelium from human pluripotent stem cells facilitates derivation of photoreceptors. Stem Cells 31, 408-414.

Terms in the title (7)： CRISPR ,  Cas9 ,  戦略 ,  ヒト ,  光受容体 ,  分化 ,  遺伝子発現プロファイル