Art

J-GLOBAL ID：201702255650435699   Reference number：17A1700650

A ubiquitin-dependent signalling axis specific for ALKBH-mediated DNA dealkylation repair

ALKBHを介したDNAの脱アルキル化修復に特異的なユビキチン依存性シグナル伝達軸

Author (22)： BRICKNER Joshua R. (Washington Univ. School of Medicine, Missouri, USA) ,  SOLL Jennifer M. (Washington Univ. School of Medicine, Missouri, USA) ,  MUDGE Miranda C. (Washington Univ. School of Medicine, Missouri, USA) ,  OYENIRAN Clement (Washington Univ. School of Medicine, Missouri, USA) ,  SULLENDER Meagan E. (Washington Univ. School of Medicine, Missouri, USA) ,  BYRUM Andrea K. (Washington Univ. School of Medicine, Missouri, USA) ,  ZHAO Yu (Washington Univ. School of Medicine, Missouri, USA) ,  MOSAMMAPARAST Nima (Washington Univ. School of Medicine, Missouri, USA) ,  LOMBARDI Patrick M. (Johns Hopkins Univ. School of Medicine, Maryland, USA) ,  BLAZOSKY Elyse (Johns Hopkins Univ. School of Medicine, Maryland, USA) ,  WOLBERGER Cynthia (Johns Hopkins Univ. School of Medicine, Maryland, USA) ,  VAGBO Cathrine B. (Norwegian Univ. Sci. and Technol., Trondheim, NOR) ,  RABE Renana (Norwegian Univ. Sci. and Technol., Trondheim, NOR) ,  SLUPPHAUG Geir (Norwegian Univ. Sci. and Technol., Trondheim, NOR) ,  VAGBO Cathrine B. (NTNU, Trondheim, NOR) ,  SLUPPHAUG Geir (NTNU, Trondheim, NOR) ,  JACKSON Jessica (St. Louis Univ. School of Medicine, Missouri, USA) ,  VINDIGNI Alessandro (St. Louis Univ. School of Medicine, Missouri, USA) ,  CORBETT Mark A. (Univ. Adelaide, South Australia, AUS) ,  GECZ Jozef (Univ. Adelaide, South Australia, AUS) ,  GECZ Jozef (South Australian Medical Res. Inst., South Australia, AUS) ,  FIELD Michael (Hunter Genetics, New South Wales, AUS)
Material： Nature (London)  (Nature (Lond))
Volume： 551  Issue： 7680  Page： 389-393  Publication year： Nov. 16, 2017 
JST Material Number： D0193B  ISSN： 0028-0836  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： *DNA ,  *Dealkylation ,  *ubiquitin ,  DNA Repair ,  DNA lesion ,  cytotoxicity ,  mutagenesis ,  genome ,  DNA double strand break ,  crosslinking ,  alkylating agent ,  drug therapy ,  tumor ,  therapy ,  chemical substance ,  Alkylation ,  cell ,  aggregate ,  nucleotide ,  RNA Polymerase II ,  RNA splicing ,  *Signal Transduction ,  DNA alkylation ,  Genetic Variation ,  molecular genetic phenomenon
Semi thesaurus term： *cellular signal transduction ,  genetic variation ,  *dealkylation ,  mutagenicity ,  Double-strand break ,  chemotherapy ,  Cancer ,  systemic therapy ,  splicing (genetics)

JST classification (4)： Nucleic acids in general  (EB04010U) ,  Addition reaction,elimination reaction  (CF02030M) ,  Proteins and peptides in general  (EB03010N) ,  Cell physiology in general  (EF02010S)

Terms in the title (6)： DNA ,  脱アルキル化 ,  修復 ,  ユビキチン ,  依存性 ,  シグナル伝達