Art

J-GLOBAL ID：201702256885127845   Reference number：17A1410247

Safety and efficacy of daclatasvir and asunaprevir in hepatitis C virus-infected patients with renal impairment

腎臓機能障害を有するC型肝炎ウイルス感染患者におけるダクラタスビルとアスナプレビルの安全性と有効性

Author (28)： Suda Goki (Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, Sapporo, Japan) ,  Nagasaka Atsushi (Department of Gastroenterology and Hepatology, Sapporo City General Hospital, Sapporo, Japan) ,  Yamamoto Yoshiya (Department of Gastroenterology and Hepatology, Hakodate City General Hospital, Hakodate, Japan) ,  Furuya Ken (Department of Gastroenterology and Hepatology, JCHO Hokkaido Hospital, Sapporo, Japan) ,  Kumagai Kenichi (Department of Gastroenterology and Hepatology, Hakodate Medical Association Hospital, Hakodate, Japan) ,  Kudo Mineo (Department of Gastroenterology and Hepatology, Sapporo Hokuyu Hospital, Sapporo, Japan) ,  Terashita Katsumi (Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, Sapporo, Japan) ,  Terashita Katsumi (Department of Gastroenterology and Hepatology, Kushiro Rosai Hospital, Kushiro, Japan) ,  Kobayashi Tomoe (Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, Sapporo, Japan) ,  Kobayashi Tomoe (Department of Gastroenterology and Hepatology, Tomakomai City Hospital, Tomakomai, Japan) ,  Tsunematsu Izumi (Department of Gastroenterology and Hepatology, Touei Hospital, Sapporo, Japan) ,  Yoshida Junichi (Department of Gastroenterology and Hepatology, JCHO Sapporo Hokushin Hospital) ,  Meguro Takashi (Department of Gastroenterology and Hepatology, Hokkaido Gastroenterology Hospital, Sapporo, Japan) ,  Kimura Megumi (Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, Sapporo, Japan) ,  Ito Jun (Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, Sapporo, Japan) ,  Umemura Machiko (Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, Sapporo, Japan) ,  Izumi Takaaki (Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, Sapporo, Japan) ,  Tsunematsu Seiji (Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, Sapporo, Japan) ,  Sato Fumiyuki (Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, Sapporo, Japan) ,  Tsukuda Yoko (Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, Sapporo, Japan) ,  Tsukuda Yoko (Department of Gastroenterology and Hepatology, Sapporo City General Hospital, Sapporo, Japan) ,  Nakai Masato (Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, Sapporo, Japan) ,  Sho Takuya (Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, Sapporo, Japan) ,  Natsuizaka Mitsuteru (Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, Sapporo, Japan) ,  Morikawa Kenichi (Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, Sapporo, Japan) ,  Ogawa Koji (Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, Sapporo, Japan) ,  Sakamoto Naoya (Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, Sapporo, Japan) ,  for the NORTE Study Group
Material： Hepatology Research  (Hepatol Res)
Volume： 47  Issue： 11  Page： 1127-1136  Publication year： Oct. 2017 
JST Material Number： W1284A  ISSN： 1386-6346  Document type： Article
Article type： 原著論文  Country of issue： Australia (AUS)  Language： ENGLISH (EN)

Thesaurus term： human ,...
Semi thesaurus term： eGFR

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Author keywords (4)： asunaprevir ,  daclatasvir ,  direct-acting antiviral ,  hepatitis C virus

JST classification (1)： Drug therapy(=pharmacotherapy)for digestive system diseases  (GH05020G)

Substance index (2)： BMS-650032 ,  BMS-790052

Reference (34)：

• Gower E, Estes C, Blach S, Razavi-Shearer K, Razavi H. Global epidemiology and genotype distribution of the hepatitis C virus infection. J Hepatol 2014; 61: S45-S57.
• Omata M, Nishiguchi S, Ueno Y et al. Sofosbuvir plus ribavirin in Japanese patients with chronic genotype 2 HCV infection: an open-label, phase 3 trial. J Viral Hepat 2014; 21: 762-8.
• Mizokami M, Yokosuka O, Takehara T et al. Ledipasvir and sofosbuvir fixed-dose combination with and without ribavirin for 12 weeks in treatment-naive and previously treated Japanese patients with genotype 1 hepatitis C: an open-label, randomised, phase 3 trial. Lancet Infect Dis 2015; 15: 645-53.
• Kumada H, Suzuki Y, Ikeda K et al. Daclatasvir plus asunaprevir for chronic HCV genotype 1b infection. Hepatology 2014; 59: 2083-91.
• Chayama K, Notsumata K, Kurosaki M et al. Randomized trial of interferon- and ribavirin-free ombitasvir/paritaprevir/ritonavir in treatment-experienced hepatitis C virus-infected patients. Hepatology 2015; 61: 1523-32.

Terms in the title (8)： 腎臓 ,  機能障害 ,  C型肝炎ウイルス感染 ,  患者 ,  ダクラタスビル ,  アスナプレビル ,  安全性 ,  有効性