Art

J-GLOBAL ID：201702257244955331   Reference number：17A1534067

Higher Adiponectin Expression Suppresses Neointimal Hyperplasia by Attenuating the Inflammatory Response Following Acceleration of Endothelialization in Damaged Areas in Adiponectin Transgenic Mice

アディポネクチントランスジェニックマウスにおけるアディポネクチン高発現は損傷部位の内皮化加速に続く炎症反応を減弱することにより新生内膜過形成を抑制する

Author (9)： OMORI Yasutoshi (Department of Medicine, Division of Cardiology, Showa University School of Medicine) ,  SUZUKI Hiroshi (Department of Medicine, Division of Cardiology, Showa University Fujigaoka Hospital) ,  SAITO Kiyomi (Department of Pharmacology, Toxicology and Therapeutics, Division of Physiology and Pathology, Showa University School of Pharmacy) ,  SHOJI Makoto (Department of Medicine, Division of Cardiology, Showa University School of Medicine) ,  ISO Yoshitaka (Showa University Research Institute for Sport and Exercise Sciences) ,  NEGORO Takaharu (Division of Pharmacology, Faculty of Pharmaceutical Sciences, Teikyo Heisei University) ,  KOBA Shinji (Department of Medicine, Division of Cardiology, Showa University School of Medicine) ,  NAKANO Yasuko (Drug treatment Labo., Clinical medicine dept., Yokohama Univ. of Pharmacy) ,  KOBAYASHI Youichi (Department of Medicine, Division of Cardiology, Showa University School of Medicine)
Material： Showa University Journal of Medical Sciences  (Showa Univ J Med Sci)
Volume： 29  Issue： 2  Page： 107-117(J-STAGE)  Publication year： 2017 
JST Material Number： L1154A  ISSN： 0915-6380  CODEN： SUMSEG  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human ,...
Semi thesaurus term： immunological reaction ,...

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Author keywords (3)： adiponectin ,  neointimal hyperplasia ,  wire injury

JST classification (1)： Basic medicine on cardiovascular system  (GJ01020K)

Reference (30)：

• 1) Tilg H, Moschen AR. Adipocytokines: mediators linking adipose tissue, inflammation and immunity. Nat Rev Immunol. 2006;6:772-783.
• 2) Nakano Y, Tobe T, Choi-Miura NH, et al. Isolation and characterization of GBP28, a novel gelatin-binding protein purified from human plasma. J Biochem. 1996;120:803-812.
• 3) Maeda K, Okubo K, Shimomura I, et al. cDNA cloning and expression of a novel adipose specific collagen-like factor, apM1 (AdiPoseMost abundant Gene transcript 1). Biochem Biophys Res Commun. 1996;221:286-289.
• 4) Scherer PE, Williams S, Fogliano M, et al. A novel serum protein similar to C1q, produced exclusively in adipocytes. J Biol Chem. 1995;270:26746-26749.
• 5) Hu E. Liang P, Spiegelman BM. AdipoQ is a novel adipose-specific gene dysregulated in obesity. J Biol Chem. 1996;271:10697-10703.

Terms in the title (8)： アディポネクチン ,  発現 ,  損傷 ,  内皮化 ,  加速 ,  炎症反応 ,  減弱 ,  新生内膜過形成