Art

J-GLOBAL ID：201702258754445532   Reference number：17A0900957

Rational design of reversible fluorescent probes for live-cell imaging and quantification of fast glutathione dynamics

生細胞イメージングおよび高速グルタチオン動力学定量化のための可逆的蛍光プローブの合理的設計

Author (7)： UMEZAWA Keitaro (Univ. Tokyo, Tokyo, JPN) ,  YOSHIDA Masafumi (Univ. Tokyo, Tokyo, JPN) ,  KAMIYA Mako (Univ. Tokyo, Tokyo, JPN) ,  KAMIYA Mako (JST-PRESTO, Saitama, JPN) ,  YAMASOBA Tatsuya (Univ. Tokyo, Tokyo, JPN) ,  URANO Yasuteru (Univ. Tokyo, Tokyo, JPN) ,  URANO Yasuteru (Japan Agency for Medical Res. and Dev. (AMED), Tokyo, JPN)
Material： Nature Chemistry  (Nat Chem)
Volume： 9  Issue： 3  Page： 279-286  Publication year： Mar. 2017 
JST Material Number： W2267A  ISSN： 1755-4330  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： *reaction kinetics ,  *oxygen heterocyclic compound ,  pathology ,  fluorescence resonance energy transfer ,  *peptide ,  cell culture ,  active oxygen ,  fluorescence spectrum ,  quantum yield ,  *probe ,  *organosilicon compound ,  aliphatic amine ,  thiol ,  aliphatic carboxylic acid ,  tripeptide ,  sulfur containing amino acid
Semi thesaurus term： Reactive Oxygen Species ,  Xanthenes ,  *rhodamine ,  fluorescent imaging ,  fluorescence probe ,  fluorescence quantum yield

JST classification (4)： Analytical reagents  (CC02030D) ,  Basic research of diagnostic drugs  (GW20010P) ,  Synthesis of drugs  (GV01030F) ,  Organosilicon compounds  (CF08030C)

Substance index (5)： 5-[[4α-[4-[10,10-Dimethyl-3-amino-6-(iminio)-6,10-dihydro-10-silaanthracene-9-yl]-3-methylbenzoylamino]cyclohexane-1β-yl]aminocarbonyl]-2-[3-(dimethylamino)-6-(dimethyliminio)-6H-xanthene-9-yl]benzoic acid methyl ester ,  5-[[4α-[4-[10,10-Dimethyl-3-amino-6-(methyliminio)-6,10-dihydro-10-silaanthracene-9-yl]-3-methylbenzoylamino]cyclohexane-1β-yl]aminocarbonyl]-2-[3-(dimethylamino)-6-(dimethyliminio)-6H-xanthene-9-yl]benzoic acid methyl ester ,  5-[[4α-[4-[9-[[(R)-2-[(S)-4-Carboxy-4-aminobutyrylamino]-3-oxo-3-(carboxymethylamino)propyl]thio]-10,10-dimethyl-3,6-diamino-9,10-dihydro-10-silaanthracene-9-yl]-3-methylbenzoylamino]cyclohexane-1β-yl]aminocarbonyl]-2-[3-(dimethylamino)-6-(dimethyliminio)-6H-xanthene-9-yl]benzoic acid 1-methyl ester ,  5-[[4α-[4-[9-[[(R)-2-[(S)-4-Carboxy-4-aminobutyrylamino]-3-oxo-3-(carboxymethylamino)propyl]thio]-10,10-dimethyl-3-(methylamino)-6-amino-9,10-dihydro-10-silaanthracene-9-yl]-3-methylbenzoylamino]cyclohexane-1β-yl]aminocarbonyl]-2-[3-(dimethylamino)-6-(dimethyliminio)-6H-xanthene-9-yl]benzoic acid 1-methyl ester ,  Glutathione

Terms in the title (6)： 生細胞イメージング ,  グルタチオン ,  動力学 ,  定量化 ,  蛍光プローブ ,  設計