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J-GLOBAL ID：201702258827076365   Reference number：17A1208027

Neural differentiation of human embryonic stem cells induced by the transgene-mediated overexpression of single transcription factors

単一転写因子の導入遺伝子媒介過剰発現により誘導されたヒト胚性幹細胞の神経分化【Powered by NICT】

Author (14)： Matsushita Misako (Department of Systems Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo 160-8582, Japan) ,  Matsushita Misako (Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo 160-8582, Japan) ,  Nakatake Yuhki (Department of Systems Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo 160-8582, Japan) ,  Arai Itaru (Department of Physiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo 160-8582, Japan) ,  Ibata Keiji (Department of Physiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo 160-8582, Japan) ,  Kohda Kazuhisa (Department of Physiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo 160-8582, Japan) ,  Goparaju Sravan K. (Department of Systems Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo 160-8582, Japan) ,  Murakami Miyako (Department of Systems Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo 160-8582, Japan) ,  Sakota Miki (Department of Systems Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo 160-8582, Japan) ,  Chikazawa-Nohtomi Nana (Department of Systems Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo 160-8582, Japan) ,  Ko Shigeru B.H. (Department of Systems Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo 160-8582, Japan) ,  Kanai Takanori (Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo 160-8582, Japan) ,  Yuzaki Michisuke (Department of Physiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo 160-8582, Japan) ,  Ko Minoru S.H. (Department of Systems Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo 160-8582, Japan)
Material： Biochemical and Biophysical Research Communications  (BBRC)
Volume： 490  Issue： 2  Page： 296-301  Publication year： 2017 
JST Material Number： B0118A  ISSN： 0006-291X  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Pluripotent human embryonic st...

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Thesaurus term： vector (genetics) ,  *transcription factor ,  immunohistochemistry ,  neuron ,  cell culture ,  *differentiation (biology) ,  versatility ,  morphology ,  mRNA ,  patch-clamp ,  Cell Differentiation ,  *neural differentiation ,  *Human Embryonic Stem Cells ,  *overexpression ,  developmental physiology ,  enol ,  aromatic ketone ,  carboxamide ,  enone ,  polynuclear aromatic compound ,  aminoalcohol ,  aminocarboxylic acid ,  keto acid ,  diketone ,  tertiary amine ,  secondary alcohol ,  hydroxy acid ,  hydroxy ketone ,  polyol

Author keywords (6)： Human embryonic stem cells ,  NEUROG ,  NEUROD ,  Neural cell differentiation ,  Transgene induction ,  Action potential

JST classification (2)： Cell physiology in general  (EF02010S) ,  Biological function  (EB03040U)

Substance index (1)： Doxycycline

Terms in the title (6)： 転写因子 ,  導入遺伝子 ,  過剰発現 ,  誘導 ,  ヒト胚性幹細胞 ,  神経分化