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J-GLOBAL ID：201702259583738316   Reference number：17A1516308

Methotrexate-related osteonecrosis of the jaw: Report of two cases

顎のメトトレキサート関連骨壊死:2症例報告

Author (4)： Komatani Toru (Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan) ,  Sonobe Junya (Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan) ,  Takahashi Katsu (Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan) ,  Bessho Kazuhisa (Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan)
Material： Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology (Web)  (J Oral Maxillofac Surg Med Pathol (Web))
Volume： 29  Issue： 6  Page： 546-549  Publication year： 2017 
JST Material Number： U0704A  ISSN： 2212-5558  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： folic acid antagonist ,...
Semi thesaurus term： stop of medication ,...

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Author keywords (3)： Methotrexate/AE ,  Osteonecrosis ,  Hyperbaric oxygen therapy

JST classification (3)： Treatment for immunologic diseases,allergic diseases.  (GD04030Y) ,  Clinical application of anti-inflammatory drugs  (GW15020E) ,  Clinical medicine on musculoskeletal system in general  (GG01030M)

Substance index (1)： Methotrexate

Reference (13)：

• Colmegna I, Ohata BR, Menard HA. Current understanding of rheumatoid arthritis therapy. Clin Pharmacol Ther 2012;91:607-20.
• Ellman MH, Hurwitz H, Thomas C, Kozloff M. Lymphoma developing in a patient with rheumatoid arthritis taking low dose weekly methotrexate. J Rheumatol 1991;18:1741-3.
• Geborek P, Bladstrom A, Turesson C, Gulfe A, Petersson I, Saxne T, et al. Tumor necrosis factor blockers do not increase overall tumor risk in patients with rheumatoid arthritis, but may be associated with an increased risk of lymphomas. Ann Rheum Dis 2005;64:699-703.
• Mishima S, Takahashi K, Tomioka T, Bessho K. Numb chin syndrome as initial manifestation of bisphosphonate-related osteomyelitis of the jaw and methotrexate-associated lymphoproliferative disorders: a rare case. Br J Oral Maxillofac Surg 2016;54:114-5.
• Zizic TM, Marcoux C, Hungerford DS, Dansereau JV, Stevens MB. Corticosteroid therapy associated with ischemic necrosis of bone in systemic lupus erythematosus. Am J Med 1985;79:596-604.

Terms in the title (4)： 顎 ,  メトトレキサート ,  骨壊死 ,  症例報告