Art

J-GLOBAL ID：201702259746524649   Reference number：17A1363207

Lack of interleukin-6 in the tumor microenvironment augments type-1 immunity and increases the efficacy of cancer immunotherapy

腫瘍微小環境におけるインターロイキン-6の欠如は1型免疫を増強し,癌免疫療法の有効性を高める

Author (17)： Ohno Yosuke (Division of Functional Immunology, Section of Disease Control, Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan) ,  Ohno Yosuke (Department of Gastroenterological Surgery I, Hokkaido University Graduate School of Medicine, Sapporo, Japan) ,  Toyoshima Yujiro (Division of Functional Immunology, Section of Disease Control, Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan) ,  Toyoshima Yujiro (Department of Gastroenterological Surgery I, Hokkaido University Graduate School of Medicine, Sapporo, Japan) ,  Yurino Hideaki (Department of Integrative Medicine for Longevity, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan) ,  Monma Norikazu (DNA Data Analysis Laboratory, National Institute of Genetics, Mishima, Japan) ,  Xiang Huihui (Division of Functional Immunology, Section of Disease Control, Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan) ,  Sumida Kentaro (Division of Functional Immunology, Section of Disease Control, Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan) ,  Kaneumi Shun (Division of Functional Immunology, Section of Disease Control, Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan) ,  Terada Satoshi (Division of Functional Immunology, Section of Disease Control, Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan) ,  Hashimoto Shinichi (Department of Integrative Medicine for Longevity, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan) ,  Ikeo Kazuho (DNA Data Analysis Laboratory, National Institute of Genetics, Mishima, Japan) ,  Homma Shigenori (Department of Gastroenterological Surgery I, Hokkaido University Graduate School of Medicine, Sapporo, Japan) ,  Kawamura Hideki (Department of Gastroenterological Surgery I, Hokkaido University Graduate School of Medicine, Sapporo, Japan) ,  Takahashi Norihiko (Department of Gastroenterological Surgery I, Hokkaido University Graduate School of Medicine, Sapporo, Japan) ,  Taketomi Akinobu (Department of Gastroenterological Surgery I, Hokkaido University Graduate School of Medicine, Sapporo, Japan) ,  Kitamura Hidemitsu (Division of Functional Immunology, Section of Disease Control, Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan)
Material： Cancer Science (Web)  (Cancer Sci (Web))
Volume： 108  Issue： 10  Page： 1959-1966  Publication year： 2017 
JST Material Number： U0505A  ISSN： 1349-7006  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： environment ,...
Semi thesaurus term： 1型免疫 ,...

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Author keywords (5)： Cytotoxic T cells ,  dendritic cells ,  interferon-γ ,  interleukin-6 ,  programmed death-ligand 1

JST classification (2)： Basic oncology in general  (GE02010R) ,  Tumors(=neoplasms)of digestive system  (GH04000D)

Reference (30)：

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• Palucka K, Banchereau J. Dendritic-cell-based therapeutic cancer vaccines. Immunity 2013; 39: 38-48.

Terms in the title (7)： 腫瘍微小環境 ,  インターロイキン-6 ,  欠如 ,  免疫 ,  増強 ,  癌免疫療法 ,  有効性