Art

J-GLOBAL ID：201702260175879005   Reference number：17A0519301

Effect of Glycemic Control on Chylomicron Metabolism and Correlation between Postprandial Metabolism of Plasma Glucose and Chylomicron in Patients with Type 2 Diabetes Treated with Basal-bolus Insulin Therapy with or without Vildagliptin

ビルダグリプチンの有り無しでの強化インスリン療法で治療される2型糖尿病患者におけるカイロミクロン代謝に対する血糖管理の影響と血漿グルコースおよびカイロミクロンの食後代謝の間の相関

Author (6)： Okajima Fumitaka (Division of Endocrinology, Department of Medicine, Chiba-Hokusoh Hospital, Nippon Medical School) ,  Okajima Fumitaka (Department of Endocrinology, Diabetes and Metabolism, Graduate School of Medicine, Nippon Medical School) ,  Emoto Naoya (Division of Endocrinology, Department of Medicine, Chiba-Hokusoh Hospital, Nippon Medical School) ,  Emoto Naoya (Department of Endocrinology, Diabetes and Metabolism, Graduate School of Medicine, Nippon Medical School) ,  Kato Katsuhito (Department of Cardiology, Chiba Hokusoh Hospital, Nippon Medical School) ,  Sugihara Hitoshi (Department of Endocrinology, Diabetes and Metabolism, Graduate School of Medicine, Nippon Medical School)
Material： Journal of Atherosclerosis and Thrombosis (Web)  (J Atheroscler Thromb (Web))
Volume： 24  Issue： 2  Page： 157-168(J-STAGE)  Publication year： 2017 
JST Material Number： U0153A  ISSN： 1880-3873  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human ,...
Semi thesaurus term： remnant lipoprotein ,...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=17A0519301&from=J-GLOBAL&jstjournalNo=U0153A") }}

Author keywords (5)： Apolipoprotein B48 ,  Postprandial metabolism ,  Glucose fluctuation ,  Glycemic control ,  Dipeptidyl peptidase-4 inhibitor

JST classification (1)： Metabolic diseases,nutritional diseases in general.  (GD05010J)

Substance index (2)： Glucose ,  Vildagliptin

Reference (43)：

• 1) The Diabetes Control and Complications Trial Research Group. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med. 1993; 329: 977-986
• 2) Ohkubo Y, Kishikawa H, Araki E, Miyata T, Isami S, Motoyoshi S, Kojima Y, Furuyoshi N and Shichiri M. Intensive insulin therapy prevents the progression of diabetic microvascular complications in Japanese patients with non-insulin-dependent diabetes mellitus: a randomized prospective 6-year study. Diabetes Res Clin Pract. 1995; 28: 103-117
• 3) Stratton IM, Adler AI, Neil HA, Matthews DR, Manley SE, Cull CA, Hadden D, Turner RC and Holman RR. Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study. BMJ. 2000; 321: 405-412
• 4) Sone H, Tanaka S, Tanaka S, Iimuro S, Oida K, Yamasaki Y, Oikawa S, Ishibashi S, Katayama S, Ohashi Y, Akanuma Y, Yamada N and Japan Diabetes Complications Study G. Serum triglyceride levels is a potent risk factor comparable to LDL cholesterol for coronary heart disease in Japanese patients with type 2 diabetes: subanalysis of the Japan Diabetes Complications Study (JDCS). J Clin Endocrinol Metab. 2011; 96: 3448-3456
• 5) UK Prospective Diabetes Study (UKPDS) Group. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet. 1998; 352: 837-853

Terms in the title (12)： ビルダグリプチン ,  強化インスリン療法 ,  治療 ,  2型糖尿病 ,  患者 ,  カイロミクロン ,  代謝 ,  血糖管理 ,  血漿 ,  グルコース ,  食後 ,  相関