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J-GLOBAL ID：201702260762787832   Reference number：17A0615255

The differentially DNA-methylated region responsible for expression of runt-related transcription factor 2

runt関連転写因子2の発現の原因となる差次的DNAメチル化領域

Author (5)： WAKITANI Shoichi (Laboratory of Veterinary Biochemistry and Molecular Biology, Faculty of Agriculture, University of Miyazaki, 1-1 Gakuenkibanadai-nishi, Miyazaki 889-2192, Japan) ,  WAKITANI Shoichi (Laboratory of Veterinary Anatomy, Faculty of Agriculture, University of Miyazaki, 1-1 Gakuenkibanadai-nishi, Miyazaki 889-2192, Japan) ,  YOKOI Daigo (Laboratory of Veterinary Biochemistry and Molecular Biology, Faculty of Agriculture, University of Miyazaki, 1-1 Gakuenkibanadai-nishi, Miyazaki 889-2192, Japan) ,  HIDAKA Yuichi (Laboratory of Veterinary Surgery, Faculty of Agriculture, University of Miyazaki, 1-1 Gakuenkibanadai-nishi, Miyazaki 889-2192, Japan) ,  NISHINO Koichiro (Laboratory of Veterinary Biochemistry and Molecular Biology, Faculty of Agriculture, University of Miyazaki, 1-1 Gakuenkibanadai-nishi, Miyazaki 889-2192, Japan)
Material： Journal of Veterinary Medical Science (Web)
Volume： 79  Issue： 2  Page： 230-237(J-STAGE)  Publication year： 2017 
JST Material Number： U1094A  ISSN： 1347-7439  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *transcription factor ,...

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Author keywords (5)： correlation analysis ,  DNA methylation ,  osteogenesis ,  promoter ,  Runx2

JST classification (2)： Skeletal system  (EJ10030R) ,  Gene expression  (EC02040Q)

Reference (27)：

• 1. Banerjee, C., Javed, A., Choi, J. Y., Green, J., Rosen, V., van Wijnen, A. J., Stein, J. L., Lian, J. B. and Stein, G. S. 2001. Differential regulation of the two principal Runx2/Cbfa1 n-terminal isoforms in response to bone morphogenetic protein-2 during development of the osteoblast phenotype. Endocrinology 142: 4026-4039.
• 2. Byon, C. H., Javed, A., Dai, Q., Kappes, J. C., Clemens, T. L., Darley-Usmar, V. M., McDonald, J. M. and Chen, Y. 2008. Oxidative stress induces vascular calcification through modulation of the osteogenic transcription factor Runx2 by AKT signaling. J. Biol. Chem. 283: 15319-15327.
• 3. Cho, Y. D., Yoon, W. J., Kim, W. J., Woo, K. M., Baek, J. H., Lee, G., Ku, Y., van Wijnen, A. J. and Ryoo, H. M. 2014. Epigenetic modifications and canonical wingless/int-1 class (WNT) signaling enable trans-differentiation of nonosteogenic cells into osteoblasts. J. Biol. Chem. 289: 20120-20128.
• 4. Ducy, P., Zhang, R., Geoffroy, V., Ridall, A. L. and Karsenty, G. 1997. Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation. Cell 89: 747-754.
• 5. Engelse, M. A., Neele, J. M., Bronckers, A. L., Pannekoek, H. and de Vries, C. J. 2001. Vascular calcification: expression patterns of the osteoblast-specific gene core binding factor alpha-1 and the protective factor matrix gla protein in human atherogenesis. Cardiovasc. Res. 52: 281-289.

Terms in the title (4)： 転写因子 ,  発現 ,  原因 ,  DNAメチル化