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J-GLOBAL ID：201702262166530682   Reference number：17A0461989

Alisol B, a triterpene from Alismatis rhizoma (dried rhizome of Alisma orientale), inhibits melanin production in murine B16 melanoma cells

沢瀉(サジオモダカAlisma orientaleの乾燥根茎)由来のトリテルペンであるアリソールBはネズミB16メラノーマ細胞のメラニン生産を阻害する

Author (6)： YOSHIDA Ichiro (Shikoku Junior Coll., Tokushima, JPN) ,  ITO Chihiro (Tokushima Univ. Graduate School, Tokushima, JPN) ,  MATSUDA Shinya (Tokushima Univ. Graduate School, Tokushima, JPN) ,  TSUJI Akihiko (Tokushima Univ. Graduate School, Tokushima, JPN) ,  YANAKA Noriyuki (Hiroshima Univ., Higashi-Hiroshima, JPN) ,  YUASA Keizo (Tokushima Univ. Graduate School, Tokushima, JPN)
Material： Bioscience, Biotechnology, and Biochemistry  (Bioscience Biotechnology & Biochemistry)
Volume： 81  Issue： 3  Page： 534-540  Publication year： Mar. 2017 
JST Material Number： G0021A  ISSN： 0916-8451  CODEN： BBBIEJ  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： Alismataceae ,...
Semi thesaurus term： Alisma ,...

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JST classification (2)： Enzyme in general  (EB09010D) ,  Plant biochemistry  (EH01050J)

Substance index (1)： Alisol B

Reference (25)：

• Costin GE, Hearing VJ. Human skin pigmentation: melanocytes modulate skin color in response to stress. FASEB J. 2007;21:976-994.
• Gilchrest BA, Park HY, Eller MS, et al. Mechanisms of ultraviolet light-induced pigmentation. Photochem Photobiol. 1996;63:1- 10.
• Hearing VJ, Tsukamoto K. Enzymatic control of pigmentation in mammals. FASEB J. 1991;5:2902-2909.
• Yasumoto K, Yokoyama K, Takahashi K, et al. Functional analysis of microphthalmia-associated transcription factor in pigment cell-specific transcription of the human tyrosinase family genes. J Biol Chem. 1997;272:503-509.
• Steingrimsson E, Copeland NG, Jenkins NA. Melanocytes and the microphthalmia transcription factor network. Annu Rev Genet. 2004;38:365-411.

Terms in the title (11)： 沢瀉 ,  オモダカ ,  Alisma ,  根茎 ,  トリテルペン ,  アリソールB ,  ネズミ ,  B16メラノーマ ,  細胞 ,  メラニン ,  阻害