Art

J-GLOBAL ID：201702265084421998   Reference number：17A0923151

Brain uptake and safety of Flutemetamol F 18 injection in Japanese subjects with probable Alzheimer’s disease, subjects with amnestic mild cognitive impairment and healthy volunteers

日本人のアルツハイマー病患者,軽度認知症患者,および健常ボランティアへのフルテメタモールF18注射の脳への取込みと安全性

Author (12)： MIKI Takami (Osaka City Univ. Hospital, Osaka, JPN) ,  MIKI Takami (Izumiotsu Municipal Hospital, Osaka, JPN) ,  SHIMADA Hiroyuki (Osaka City Univ. Hospital, Osaka, JPN) ,  KIM Jae-Seung (Asan Medical Center, Seoul, KOR) ,  YAMAMOTO Yasuji (Kobe Univ. Hospital, Hyogo Prefecture, JPN) ,  SUGINO Masakazu (Aino Hospital, Center of Geriatric Somato-Psychological Care, Osaka, JPN) ,  KOWA Hisatomo (Kobe Univ. Hospital, Hyogo Prefecture, JPN) ,  HEURLING Kerstin (GE Healthcare, Uppsala, SWE) ,  HEURLING Kerstin (Uppsala Univ., Uppsala, SWE) ,  ZANETTE Michelle (GE Healthcare, MA, USA) ,  SHERWIN Paul F. (GE Healthcare, MA, USA) ,  SENDA Michio (Inst. Biomedical Res. and Innovation Hospital, Hyogo Prefecture, JPN)
Material： Annals of Nuclear Medicine  (Ann Nucl Med)
Volume： 31  Issue： 3  Page： 260-272  Publication year： Apr. 2017 
JST Material Number： X0838A  ISSN： 0914-7187  CODEN： ANMEEX  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Thesaurus term： *Alzheimer disease ,...
Semi thesaurus term： *Mild dementia ,...

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JST classification (2)： Neurologic diagnosis  (GN02000H) ,  Clinical application of diagnostic drugs  (GW20020A)

Substance index (1)： Flutemetamol

Reference (24)：

• Matsui Y, Tanizaki Y, Arima H, Yonemoto K, Doi Y, Ninomiya T, et al. Incidence and survival of dementia in a general population of Japanese elderly: the Hisayama study. J Neurol Neurosurg Psychiatry. 2009;80(4):366-70.
• Yamada M, Mimori Y, Kasagi F, Miyachi T, Ohshita T, Sudoh S, et al. Incidence of dementia, Alzheimer disease, and vascular dementia in a Japanese population: Radiation Effects Research Foundation adult health study. Neuroepidemiology. 2008;30(3):152-60.
• Fratiglioni L, Launer LJ, Andersen K, Breteler MM, Copeland JR, Dartigues JF, et al. Incidence of dementia and major subtypes in Europe: a collaborative study of population-based cohorts. Neurologic Diseases in the Elderly Research Group. Neurology. 2000;54(11 Suppl 5):S10-5.
• National Institute on Aging. About Alzheimer’s disease: diagnosis. http://www.nia.nih.gov/alzheimers/topics/diagnosis. Accessed 5 Sept 2014.
• Ikonomovic MD, Klunk WE, Abrahamson EE, Mathis CA, Price JC, Tsopelas ND, et al. Post-mortem correlates of in vivo PiB-PET amyloid imaging in a typical case of Alzheimer’s disease. Brain. 2008;131(Pt 6):1630-45.

Terms in the title (10)： 日本人 ,  アルツハイマー病 ,  患者 ,  軽度 ,  認知症患者 ,  健常ボランティア ,  注射 ,  脳 ,  取込み ,  安全性