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J-GLOBAL ID：201702267134103681   Reference number：17A1967046

NOAEL-dose of a neonicotinoid pesticide, clothianidin, acutely induce anxiety-related behavior with human-audible vocalizations in male mice in a novel environment

ネオニコチノイド系農薬のNOAEL量,クロチアニジン,は新規環境における雄マウスにおけるヒト可聴発声と不安関連行動を誘発する急性【Powered by NICT】

Author (12)： Hirano Tetsushi (Laboratory of Animal Molecular Morphology, Department of Animal Science, Graduate School of Agricultural Science, Kobe University, Kobe, Hyogo 657-8501, Japan) ,  Yanai Shogo (Laboratory of Animal Molecular Morphology, Department of Animal Science, Graduate School of Agricultural Science, Kobe University, Kobe, Hyogo 657-8501, Japan) ,  Takada Tadashi (Laboratory of Animal Molecular Morphology, Department of Animal Science, Graduate School of Agricultural Science, Kobe University, Kobe, Hyogo 657-8501, Japan) ,  Yoneda Naoki (Laboratory of Animal Molecular Morphology, Department of Animal Science, Graduate School of Agricultural Science, Kobe University, Kobe, Hyogo 657-8501, Japan) ,  Omotehara Takuya (Laboratory of Animal Molecular Morphology, Department of Animal Science, Graduate School of Agricultural Science, Kobe University, Kobe, Hyogo 657-8501, Japan) ,  Kubota Naoto (Laboratory of Animal Molecular Morphology, Department of Animal Science, Graduate School of Agricultural Science, Kobe University, Kobe, Hyogo 657-8501, Japan) ,  Minami Kiichi (Laboratory of Animal Molecular Morphology, Department of Animal Science, Graduate School of Agricultural Science, Kobe University, Kobe, Hyogo 657-8501, Japan) ,  Yamamoto Anzu (Laboratory of Animal Molecular Morphology, Department of Animal Science, Graduate School of Agricultural Science, Kobe University, Kobe, Hyogo 657-8501, Japan) ,  Mantani Youhei (Laboratory of Histophysiology, Department of Animal Science, Graduate School of Agricultural Science, Kobe University, Kobe, Hyogo 657-8501, Japan) ,  Yokoyama Toshifumi (Laboratory of Animal Molecular Morphology, Department of Animal Science, Graduate School of Agricultural Science, Kobe University, Kobe, Hyogo 657-8501, Japan) ,  Kitagawa Hiroshi (Laboratory of Histophysiology, Department of Animal Science, Graduate School of Agricultural Science, Kobe University, Kobe, Hyogo 657-8501, Japan) ,  Hoshi Nobuhiko (Laboratory of Animal Molecular Morphology, Department of Animal Science, Graduate School of Agricultural Science, Kobe University, Kobe, Hyogo 657-8501, Japan)
Material： Toxicology Letters  (Toxicol Lett)
Volume： 282  Page： 57-63  Publication year： 2018 
JST Material Number： E0034B  ISSN： 0378-4274  CODEN： TOLED5  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Neonicotinoids are novel syste...

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Thesaurus term： Insecta ,  immunological reaction ,  nicotinic receptor ,  *vocalization ,  thalamus ,  cell count ,  Mammalia ,  paraventricular nucleus ,  hippocampus ,  dentate gyrus ,  *human(primates)
Semi thesaurus term： ストレス応答 ,  アゴニスト ,  *無毒性量 , 【Automatic Indexing@JST】

Author keywords (6)： Neonicotinoid ,  Clothianidin ,  Neurobehavioral effect ,  Elevated plus-maze test ,  Anxiety-related behavior ,  Human-audible vocalization

JST classification (1)： Toxicity of organic compounds  (GZ02030Y)

Substance index (1)： Clothianidin

Terms in the title (9)： ネオニコチノイド系農薬 ,  NOAEL ,  クロチアニジン ,  環境 ,  マウス ,  ヒト ,  発声 ,  行動 ,  誘発