Art

J-GLOBAL ID：201702267479355972   Reference number：17A1440646

Neutron structure of the T26H mutant of T4 phage lysozyme provides insight into the catalytic activity of the mutant enzyme and how it differs from that of wild type

T4ファージリゾチームのT26H変異体の中性子構造は変異酵素の触媒活性への洞察を提供するとそれは野生型のそれと異なるか【Powered by NICT】

Author (8)： Hiromoto Takeshi (Quantum Beam Science Center, Japan Atomic Energy Agency, Tokai, Ibaraki, 319-1195, Japan) ,  Meilleur Flora (Neutron Sciences Directorate, Oak Ridge National Laboratory, Oak Ridge, Tennessee, 37831) ,  Meilleur Flora (Department of Molecular and Structural Biochemistry, North Carolina State University, Raleigh, North Carolina, 27695) ,  Shimizu Rumi (Quantum Beam Science Research Directorate, National Institutes for Quantum and Radiological Science and Technology, Tokai, Ibaraki, 319-1106, Japan) ,  Shibazaki Chie (Quantum Beam Science Research Directorate, National Institutes for Quantum and Radiological Science and Technology, Tokai, Ibaraki, 319-1106, Japan) ,  Adachi Motoyasu (Quantum Beam Science Research Directorate, National Institutes for Quantum and Radiological Science and Technology, Tokai, Ibaraki, 319-1106, Japan) ,  Tamada Taro (Quantum Beam Science Research Directorate, National Institutes for Quantum and Radiological Science and Technology, Tokai, Ibaraki, 319-1106, Japan) ,  Kuroki Ryota (Quantum Beam Science Center, Japan Atomic Energy Agency, Tokai, Ibaraki, 319-1195, Japan)
Material： Protein Science
Volume： 26  Issue： 10  Page： 1953-1963  Publication year： 2017 
JST Material Number： W2730A  ISSN： 0961-8368  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： T4 phage lysozyme is an invert...

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Thesaurus term： interaction ,  active site ,  binding site ,  *catalyst ,  deprotonation ,  hydrolysis ,  *T4 phage ,  *catalytic activity ,  internuclear distance ,  water molecule ,  *lysozyme ,  *wild type ,  deuterium ,  substrate(biochemistry) ,  protonation

Author keywords (4)： lysozyme ,  hydrolysis ,  perdeuteration ,  neutron crystallography

JST classification (1)： Enzyme in general  (EB09010D)

Terms in the title (8)： T4ファージ ,  リゾチーム ,  変異体 ,  中性子 ,  変異酵素 ,  触媒活性 ,  洞察 ,  野生型