Co-administration of dexamethasone increases severity and accelerates onset day of neutropenia in bladder cancer patients on methotrexate, vinblastine, adriamycin and cisplatin chemotherapy: a retrospective cohort study

ITAI Shingo; SUGA Yukio; HARA Yusuke; IZUMI Kouji; MAEDA Yuji; KITAGAWA Yasuhide; ISHIZAKI Junko; SHIMADA Tsutomu; MIZOKAMI Atsushi; SAI Yoshimichi

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J-GLOBAL ID：201702269496980084 Reference number：17A1085069

Co-administration of dexamethasone increases severity and accelerates onset day of neutropenia in bladder cancer patients on methotrexate, vinblastine, adriamycin and cisplatin chemotherapy: a retrospective cohort study

メトトレキセート,ビンブラスチン,アドリアマイシンおよびシスプラチン化学療法の膀胱癌患者においてデキサメタゾンの同時投与は重症度を上昇させ,好中球減少の開始日を早める:後向きコホート研究

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Material：
Volume： 3 Issue： Jan Page： 3:3 (WEB ONLY) Publication year： Jan. 2017
JST Material Number： U1100A ISSN： 2055-0294 Document type： Article
Article type：原著論文 Country of issue： United Kingdom (GBR) Language： ENGLISH (EN)

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Drug therapy(=pharmacotherapy)for tumors , Basic research of antitumor(=antineoplastic)drugs , Clinical application of drugs acting on digestive system , Clinical application of antitumor(=antineoplastic)drugs , Hematologic diseases

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Reference (24)：

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Loehrer Sr PJ, Einhorn LH, Elson PJ, Crawford ED, Kuebler P, Tannock I, et al. A Randomized comparison of cisplatin alone or in combination with methotrexate, vinvlastin, and doxorubicin in patients with metastatic urothelial carcinoma: a cooperative group study. J Clin Oncol. 1992;10:1066-73.
Sternberg CN, Yagoda A, Scher HI, Watoson RC, Geller N, Herr HW, et al. Methotrexate, vinblastine, doxorubicin, and cisplatin for advanced transitional cell carcinoma of the urothelium. Efficacy and patterns of response and relapse. Cancer. 1989;64:2448-58.
Morran C, Smith DC, Anderson DA, McArdle CS. Incidence of nausea and vomiting with cytotoxic chemotherapy: a prospective randomized trial of antiemetics. Br Med J. 1979;1:1323-4.
Basch E, Prestrud AA, Hesketh PJ, Kris MG, Feyer PC, Somerfield MR, et al. Antiemetics: American Society of Clinical Oncology clinical practice guideline update. J Clin Oncol. 2011;29:4189-98.

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