Art

J-GLOBAL ID：201702270415214408   Reference number：17A0701349

A novel all-in-one intraoperative genotyping system for IDH1-mutant glioma

IDH1-突然変異神経膠腫の新しい一体型の術中ジェノタイピングシステム

Author (19)： OHKA Fumiharu (Nagoya Univ., Nagoya, JPN) ,  YAMAMICHI Akane (Nagoya Univ., Nagoya, JPN) ,  YAMAMICHI Akane (Mie Univ., Tsu, JPN) ,  KURIMOTO Michihiro (Nagoya Univ., Nagoya, JPN) ,  MOTOMURA Kazuya (Nagoya Univ., Nagoya, JPN) ,  TANAHASHI Kuniaki (Nagoya Univ., Nagoya, JPN) ,  SUZUKI Hiromichi (Nagoya Univ., Nagoya, JPN) ,  SUZUKI Hiromichi (Kyoto Univ., Kyoto, JPN) ,  AOKI Kosuke (Nagoya Univ., Nagoya, JPN) ,  AOKI Kosuke (Kyoto Univ., Kyoto, JPN) ,  DEGUCHI Shoichi (Nagoya Univ., Nagoya, JPN) ,  CHALISE Lushun (Nagoya Univ., Nagoya, JPN) ,  HIRANO Masaki (Nagoya Univ., Nagoya, JPN) ,  KATO Akira (Nagoya Univ., Nagoya, JPN) ,  NISHIMURA Yusuke (Nagoya Univ., Nagoya, JPN) ,  HARA Masahito (Nagoya Univ., Nagoya, JPN) ,  KATO Yukinari (Tohoku Univ. Graduate School of Medicine, Sendai, JPN) ,  WAKABAYASHI Toshihiko (Nagoya Univ., Nagoya, JPN) ,  NATSUME Atsushi (Nagoya Univ., Nagoya, JPN)
Material： Brain Tumor Pathology  (Brain Tumor Pathol)
Volume： 34  Issue： 2  Page： 91-97  Publication year： 2017 
JST Material Number： L2617A  ISSN： 1433-7398  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Thesaurus term： human ,...
Semi thesaurus term： *genetic variation ,...

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JST classification (3)： Diagnosis of tumors(=neoplasms)  (GE03020J) ,  Gene manipulation  (EC02050B) ,  Tumors(=neoplasms)of nervous system  (GN04000V)

Reference (25)：

• Suzuki H, Aoki K, Chiba K, Sato Y, Shiozawa Y, Shiraishi Y, Shimamura T, Niida A, Motomura K, Ohka F et al (2015) Mutational landscape and clonal architecture in grade II and III gliomas. Nat Genet 47:458-468
• Brat DJ, Verhaak RG, Aldape KD, Yung WK, Salama SR, Cooper LA, Rheinbay E, Miller CR, Vitucci M, Morozova O et al (2015) Comprehensive, integrative genomic analysis of diffuse lower-grade gliomas. N Engl J Med 372:2481-2498
• Ceccarelli M, Barthel FP, Malta TM, Sabedot TS, Salama SR, Murray BA, Morozova O, Newton Y, Radenbaugh A, Pagnotta SM et al (2016) Molecular profiling reveals biologically discrete subsets and pathways of progression in diffuse glioma. Cell 164:550-563
• Yan H, Parsons DW, Jin G, McLendon R, Rasheed BA, Yuan W, Kos I, Batinic-Haberle I, Jones S, Riggins GJ et al (2009) IDH1 and IDH2 mutations in gliomas. N Engl J Med 360:765-773
• Kurimoto M, Suzuki H, Aoki K, Ohka F, Kondo G, Motomura K, Iijima K, Yamamichi A, Ranjit M, Wakabayashi T et al (2016) Rapid sensitive analysis of IDH1 mutation in lower-grade gliomas by automated genetic typing involving a quenching probe. Cancer Invest 34:12-15

Terms in the title (3)： 突然変異 ,  神経膠腫 ,  ジェノタイピング