Art

J-GLOBAL ID：201702271213114371   Reference number：17A0920443

HALOGENATION OF DIMETHYL INDOLE-2,3-DICARBOXYLATES USING PhI(OAc)2 AND ALKALI METAL HALIDE

PhI(OAc)₂およびアルカリ金属ハロゲン化物を用いたインドール-2,3-ジカルボン酸ジメチル類のハロゲン化

Author (9)： MIKI Yasuyoshi (Kindai Univ., Osaka, JPN) ,  MIKI Yasuyoshi (Res. Organization of Sci. and Technol., Res. Center for Drug Discovery and Pharmaceutical Sci., Shiga, JPN) ,  HIRATA Yukari (Kindai Univ., Osaka, JPN) ,  MAKINO Noriko (Kindai Univ., Osaka, JPN) ,  HIROSE Yuuka (Kindai Univ., Osaka, JPN) ,  NOGATA Misa (Kindai Univ., Osaka, JPN) ,  NAKAMURA Akira (Kindai Univ., Osaka, JPN) ,  HAMAMOTO Hiromi (Meijo Univ., Nagoya, JPN) ,  MAEGAWA Tomohiro (Kindai Univ., Osaka, JPN)
Material： Heterocycles  (International Journal for Reviews and Communications in Heterocyclic Chemistry)
Volume： 94  Issue： 7  Page： 1269-1279  Publication year： Jul. 01, 2017 
JST Material Number： S0966A  ISSN： 0385-5414  CODEN： HTCYAM  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： chemical synthesis ,  *bromination ,  *iodination ,  regiospecific reaction ,  functional group protection ,  lithium bromide ,  lithium iodide ,  Lewis acid ,  *nitrogen heterocyclic compound ,  *polynuclear aromatic compound ,  dicarboxylic acid ,  carboxylate(ester) ,  aromatic halogen compound ,  substituent effect
Semi thesaurus term： *indoles ,  regioselective reaction

JST classification (1)： Condensed derivatives of pyrroles  (CF07077C)

Substance index (11)： 1H-Indole-2,3-dicarboxylic acid dimethyl ester ,  1-Phenylsulfonyl-1H-indole-2,3-dicarboxylic acid dimethyl ester ,  1-(Phenylsulfonyl)-5-iodo-1H-indole-2,3-dicarboxylic acid dimethyl ester ,  1-(Phenylsulfonyl)-6-iodo-1H-indole-2,3-dicarboxylic acid dimethyl ester ,  1-Benzyl-1H-indole-2,3-dicarboxylic acid dimethyl ester ,  1-Benzyl-5-iodo-1H-indole-2,3-dicarboxylic acid dimethyl ester ,  1-Benzyl-6-iodo-1H-indole-2,3-dicarboxylic acid dimethyl ester ,  5-Iodo-1H-indole-2,3-dicarboxylic acid dimethyl ester ,  6-Iodo-1H-indole-2,3-dicarboxylic acid dimethyl ester ,  Trifluoroboron・diethyl ether ,  Phenyldiacetoxyiodine(III)

Reference (15)：

• (a) 'Modem Heterocyclic Chemistry,' Vol. 1, ed. by J. Alvarez-Builla, J. J. Vaquero, and J. Barluenga, Wiley-VCH, Weinheim, 2011; (b) 'Heterocyclic Scaffold II: Reactions and Applications of Indoles,' ed. by G. W. Gribble, Springer, Heidelberg, 2010; (c) 'Heterocyclic Chemistry in Drug Discovery,' ed. by J. J. Li, John Wiley & Sons, Inc., Hoboken, New Jersey, 2013.
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Terms in the title (6)： PHI ,  アルカリ金属ハロゲン化物 ,  インドール ,  ジカルボン酸 ,  ジメチル ,  ハロゲン化