Art

J-GLOBAL ID：201702271974369729   Reference number：17A1697907

Mutation status of RAD51C, PALB2 and BRIP1 in 100 Japanese familial breast cancer cases without BRCA1 and BRCA2 mutations

BRCA1とBRCA2に変異のない100の日本人家族性乳癌症例におけるRAD51CとPALB2とBRIP1の変異状態

Author (15)： Sato Katsutoshi (Clinical Genetic Oncology, Cancer Institute Hospital, Japanese Foundation of Cancer Research, Tokyo, Japan) ,  Koyasu Mio (Clinical Genetic Oncology, Cancer Institute Hospital, Japanese Foundation of Cancer Research, Tokyo, Japan) ,  Nomura Sachio (Clinical Genetic Oncology, Cancer Institute Hospital, Japanese Foundation of Cancer Research, Tokyo, Japan) ,  Nomura Sachio (Translational Research Support, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan) ,  Sato Yuri (Clinical Genetic Oncology, Cancer Institute Hospital, Japanese Foundation of Cancer Research, Tokyo, Japan) ,  Kita Mizuho (Clinical Genetic Oncology, Cancer Institute Hospital, Japanese Foundation of Cancer Research, Tokyo, Japan) ,  Ashihara Yuumi (Clinical Genetic Oncology, Cancer Institute Hospital, Japanese Foundation of Cancer Research, Tokyo, Japan) ,  Adachi Yasue (Clinical Genetic Oncology, Cancer Institute Hospital, Japanese Foundation of Cancer Research, Tokyo, Japan) ,  Ohno Shinji (Department of Surgical Oncology, Breast Oncology Center, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan) ,  Iwase Takuji (Department of Surgical Oncology, Breast Oncology Center, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan) ,  Kitagawa Dai (Department of Surgical Oncology, Breast Oncology Center, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan) ,  Nakashima Eri (Department of Surgical Oncology, Breast Oncology Center, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan) ,  Yoshida Reiko (Clinical Genetic Oncology, Cancer Institute Hospital, Japanese Foundation of Cancer Research, Tokyo, Japan) ,  Miki Yoshio (Division of Medical Genomics, Department of Molecular Genetics, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan) ,  Arai Masami (Clinical Genetic Oncology, Cancer Institute Hospital, Japanese Foundation of Cancer Research, Tokyo, Japan)
Material： Cancer Science (Web)  (Cancer Sci (Web))
Volume： 108  Issue： 11  Page： 2287-2294  Publication year： 2017 
JST Material Number： U0505A  ISSN： 1349-7006  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： human ,...
Semi thesaurus term： genetic variation ,...

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Author keywords (5)： BRIP1 ,  hereditary breast cancer ,  Japanese ,  PALB2 ,  RAD51C

JST classification (1)： Clinical oncology in general  (GE03010Y)

Reference (49)：

• Ford D, Easton DF, Stratton M et al. Genetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in breast cancer families. The Breast Cancer Linkage Consortium. Am J Hum Genet 1998; 62: 676-89.
• Sugano K, Nakamura S, Ando J et al. Cross-sectional analysis of germline BRCA1 and BRCA2 mutations in Japanese patients suspected to have hereditary breast/ovarian cancer. Cancer Sci 2008; 99: 1967-76.
• Daly MB, Pilarski R, Berry M et al. NCCN guidelines insights: genetic/familial high-risk assessment: breast and ovarian, Version 2.2017. J Natl Compr Canc Netw 2017; 15: 9-20.
• Somyajit K, Subramanya S, Nagaraju G. RAD51C: a novel cancer susceptibility gene is linked to Fanconi anemia and breast cancer. Carcinogenesis 2010; 31: 2031-8.
• Sigurdsson S, Van Komen S, Bussen W, Schild D, Albala JS, Sung P. Mediator function of the human Rad51B-Rad51C complex in Rad51/RPA-catalyzed DNA strand exchange. Genes Dev 2001; 15: 3308-18.

Terms in the title (7)： BRCA1 ,  BRCA2 ,  変異 ,  日本人 ,  家族性乳癌 ,  症例 ,  PALB2