Art

J-GLOBAL ID：201702273253712602   Reference number：17A1483722

SB223412, a neurokinin-3 receptor-selective antagonist, suppresses testosterone secretion in male guinea pigs

ニューロキニン-3受容体選択的きっ抗薬,SB223412は雄モルモットにおけるテストステロン分泌を抑制する【Powered by NICT】

Author (11)： Nakamura Sho (Laboratory of Theriogenology, Department of Veterinary Medical Sciences, The University of Tokyo, Tokyo 113-8657, Japan) ,  Ito Yoshiko (Laboratory of Theriogenology, Department of Veterinary Medical Sciences, The University of Tokyo, Tokyo 113-8657, Japan) ,  Yamamoto Koki (Laboratory of Bioorganic Medicinal Chemistry & Chemogenomics, Graduate School of Pharmaceutical Sciences, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan) ,  Takahashi Chudai (Laboratory of Theriogenology, Department of Veterinary Medical Sciences, The University of Tokyo, Tokyo 113-8657, Japan) ,  Dai Mingdao (Laboratory of Theriogenology, Department of Veterinary Medical Sciences, The University of Tokyo, Tokyo 113-8657, Japan) ,  Tanahashi Miyu (Laboratory of Theriogenology, Department of Veterinary Medical Sciences, The University of Tokyo, Tokyo 113-8657, Japan) ,  Uenoyama Yoshihisa (Laboratory of Reproductive Science, Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya 464-8601, Japan) ,  Tsukamura Hiroko (Laboratory of Reproductive Science, Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya 464-8601, Japan) ,  Oishi Shinya (Laboratory of Bioorganic Medicinal Chemistry & Chemogenomics, Graduate School of Pharmaceutical Sciences, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan) ,  Maeda Kei-ichiro (Laboratory of Theriogenology, Department of Veterinary Medical Sciences, The University of Tokyo, Tokyo 113-8657, Japan) ,  Matsuda Fuko (Laboratory of Theriogenology, Department of Veterinary Medical Sciences, The University of Tokyo, Tokyo 113-8657, Japan)
Material： Theriogenology
Volume： 102  Page： 183-189  Publication year： 2017 
JST Material Number： A1189A  ISSN： 0093-691X  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Guinea pigs are important zoo ...

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Thesaurus term： neuron ,  luteinizing hormone ,  plasma(blood) ,  *guinea pig ,  *neurokinin ,  in vitro experiment ,  subcutaneous administration ,  *receptor ,  affinity ,  arcuate nucleus ,  gonadotropin-releasing hormone ,  *secretion(physiology) ,  oral administration ,  testis ,  steroid ,  enone ,  alicyclic alcohol ,  alicyclic ketone

Author keywords (5)： NK3R ,  KNDy neurons ,  Kisspeptin ,  Dynorphin A ,  Contraceptive

JST classification (2)： Physiology and anatomy of endocrine system  (EJ08000J) ,  Bioactive peptides  (EB08100U)

Substance index (1)： Testosterone

Terms in the title (6)： ニューロキニン ,  受容体 ,  きっ抗薬 ,  モルモット ,  テストステロン ,  分泌