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J-GLOBAL ID：201702275464427510   Reference number：17A0619698

Kisspeptin expression is decreased in the arcuate nucleus of hypothyroid female rats with irregular estrus cycles

不規則な発情周期を有する甲状腺機能低下性の雌ラットの弓状核においてキスペプチンの発現が減少する

Author (6)： Tomori Yuji (Department of Anatomy and Neurobiology, Graduate School of Medicine, Nippon Medical School, Bunkyo-ku, Tokyo, Japan) ,  Tomori Yuji (Department of Orthopedic Surgery, Graduate School of Medicine, Nippon Medical School, Bunkyo-ku, Tokyo, Japan) ,  Takumi Ken (Department of Anatomy and Neurobiology, Graduate School of Medicine, Nippon Medical School, Bunkyo-ku, Tokyo, Japan) ,  Iijima Norio (Department of Anatomy and Neurobiology, Graduate School of Medicine, Nippon Medical School, Bunkyo-ku, Tokyo, Japan) ,  Takai Shinro (Department of Orthopedic Surgery, Graduate School of Medicine, Nippon Medical School, Bunkyo-ku, Tokyo, Japan) ,  Ozawa Hitoshi (Department of Anatomy and Neurobiology, Graduate School of Medicine, Nippon Medical School, Bunkyo-ku, Tokyo, Japan)
Material： Neuroscience Research  (神経科学)
Volume： 117  Page： 35-41  Publication year： Apr. 2017 
JST Material Number： D0210C  ISSN： 0168-0102  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： rat ,...
Semi thesaurus term： *kisspeptin ,...

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Author keywords (4)： Hypothyroidism ,  Kisspeptin ,  Propylthiouracil ,  Thyroid hormone

JST classification (1)： Basic medicine on endocrine system  (GL01020Q)

Substance index (2)： Thyroxin ,  Estradiol

Reference (49)：

• Adachi, S., Yamada, S., Takatsu, Y., Matsui, H., Kinoshita, M., Takase, K., Sugiura, H., Ohtaki, T., Matsumoto, H., Uenoyama, Y., Tsukamura, H., Inoue, K., Maeda, K., 2007. Involvement of anteroventral periventricular metastin/kisspeptin neurons in estrogen positive feedback action on luteinizing hormone release in female rats. J. Reprod. Dev. 53, 367-378.
• Araujo-Lopes, R., Crampton, J.R., Aquino, N.S., Miranda, R.M., Kokay, I.C., Reis, A.M., Franci, C.R., Grattan, D.R., Szawka, RE., 2014. Prolactin regulates kisspeptin neurons in the arcuate nucleus to suppress LH secretion in female rats. Endocrinology 155, 1010-1020.
• Armada-Dias, L, Carvalho, JJ., Breitenbach, M.M., Franci, C.R., Moura, E.G., 2001. Is the infertility in hypothyroidism mainly due to ovarian or pituitary functional changes? Braz. J. Med. Biol. Res. 34, 1209-1215.
• Bassett, J.H., Williams, G.R., 2016. Role of thyroid hormones in skeletal development and bone maintenance. Endocr. Rev. 37, 135-187.
• Binita, G., Suprava, P., Mainak, C., Koner, B.C., Alpana, S., 2009. Correlation of prolactin and thyroid hormone concentration with menstrual patterns in infertile women. J. Reprod. Infertil. 10, 207-212.

Terms in the title (7)： 発情周期 ,  甲状腺機能低下 ,  雌 ,  ラット ,  弓状核 ,  キスペプチン ,  発現