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J-GLOBAL ID：201702276290046573   Reference number：17A0372984

Cocoa bean (Theobroma cacao L.) phenolic extracts as PTP1B inhibitors, hepatic HepG2 and pancreatic β-TC3 cell cytoprotective agents and their influence on oxidative stress in rats

PTP1B阻害剤,肝臓H epG2およびすい臓TC3細胞細胞保護剤とその影響ラットにおける酸化ストレスに対するとしてのカカオ豆(Theobroma cacaoL.)フェノール類抽出物【Powered by NICT】

Author (10)： Zyzelewicz Dorota (Institute of Food Technology and Analysis, Faculty of Biotechnology and Food Sciences, Lodz University of Technology, 90-924 Lodz, Poland) ,  Zaklos-Szyda Malgorzata (Institute of Technical Biochemistry, Faculty of Biotechnology and Food Sciences, Lodz University of Technology, 90-924 Lodz, Poland) ,  Juskiewicz Jerzy (Department of Biological Functions of Food, Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, 10-748 Olsztyn, Poland) ,  Bojczuk Malgorzata (Institute of Food Technology and Analysis, Faculty of Biotechnology and Food Sciences, Lodz University of Technology, 90-924 Lodz, Poland) ,  Oracz Joanna (Institute of Food Technology and Analysis, Faculty of Biotechnology and Food Sciences, Lodz University of Technology, 90-924 Lodz, Poland) ,  Budryn Grazyna (Institute of Food Technology and Analysis, Faculty of Biotechnology and Food Sciences, Lodz University of Technology, 90-924 Lodz, Poland) ,  Miskiewicz Karolina (Institute of Food Technology and Analysis, Faculty of Biotechnology and Food Sciences, Lodz University of Technology, 90-924 Lodz, Poland) ,  Krysiak Wieslawa (Institute of Food Technology and Analysis, Faculty of Biotechnology and Food Sciences, Lodz University of Technology, 90-924 Lodz, Poland) ,  Zdunczyk Zenon (Department of Biological Functions of Food, Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, 10-748 Olsztyn, Poland) ,  Jurgonski Adam (Department of Biological Functions of Food, Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, 10-748 Olsztyn, Poland)
Material： Food Research International  (Food Res Int)
Volume： 89  Issue： P2  Page： 946-957  Publication year： 2016 
JST Material Number： D0633A  ISSN： 0963-9969  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： Recently attention has been fo...

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Thesaurus term： Type 2 diabetes mellitus ,  biological activity ,  human ,  cocoa ,  hepatocyte ,  *Theobroma cacao ,  *oxidative stress ,  antioxidation ,  Obesity ,  *cacao bean ,  chemical substance ,  insulin ,  hypoglycemic action ,  antioxidant capacity ,  *educt ,  hypoglycemic drug ,  metabolic drug ,  carbohydrate metabolic drug ,  drug

Author keywords (5)： Cocoa bean extract (CBE) ,  Phenolic compounds ,  Centrifugal partition chromatography (CPC) ,  LC-MS/MS ,  Biological activity

JST classification (2)： Food chemistry,nutritional value  (FJ01020J) ,  Confectionery  (FJ08000K)

Terms in the title (12)： PTP1B ,  阻害剤 ,  肝臓 ,  すい臓 ,  細胞 ,  細胞保護 ,  ラット ,  酸化ストレス ,  カカオ豆 ,  Theobroma ,  フェノール類 ,  抽出物