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J-GLOBAL ID：201702277460655672   Reference number：17A1239436

The methylation status and expression of human telomerase reverse transcriptase is significantly high in oral carcinogenesis

ヒトテロメラーゼ逆転写酵素のメチル化状態と発現は口腔発癌において有意に高い【Powered by NICT】

Author (11)： Haraguchi Kazuya (Division of Oral and Maxillofacial Surgery, Department of Science of Physical Functions, Kyushu Dental University, Kitakyushu, Japan) ,  Yada Naomi (Division of Oral Pathology, Department of Health Promotion, Kyushu Dental University, Kitakyushu, Japan) ,  Sato Shinobu (Department of Applied Chemistry, Research Center for Bio-microsensing Technology, Kyushu Institute of Technology, Kitakyushu, Japan) ,  Habu Manabu (Division of Oral and Maxillofacial Surgery, Department of Science of Physical Functions, Kyushu Dental University, Kitakyushu, Japan) ,  Hayakawa Mana (Division of Oral and Maxillofacial Surgery, Department of Science of Physical Functions, Kyushu Dental University, Kitakyushu, Japan) ,  Takahashi Osamu (Division of Oral and Maxillofacial Surgery, Department of Science of Physical Functions, Kyushu Dental University, Kitakyushu, Japan) ,  Sasaguri Masaaki (Division of Oral and Maxillofacial Surgery, Department of Science of Physical Functions, Kyushu Dental University, Kitakyushu, Japan) ,  Takenaka Shigeori (Department of Applied Chemistry, Research Center for Bio-microsensing Technology, Kyushu Institute of Technology, Kitakyushu, Japan) ,  Yoshioka Izumi (Division of Oral Medicine, Department of Science of Physical Functions, Kyushu Dental University, Kitakyushu, Japan) ,  Matsuo Kou (Division of Oral Pathology, Department of Health Promotion, Kyushu Dental University, Kitakyushu, Japan) ,  Tominaga Kazuhiro (Division of Oral and Maxillofacial Surgery, Department of Science of Physical Functions, Kyushu Dental University, Kitakyushu, Japan)
Material： APMIS  (Acta Pathologica, Microbiologica et Immunologica Scandinavica)
Volume： 125  Issue： 9  Page： 797-807  Publication year： 2017 
JST Material Number： D0486D  ISSN： 0903-4641  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： Telomerase activity is present...

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Thesaurus term： *Carcinogenesis ,  immunohistochemistry ,  Mouth Mucosa ,  *Methylation ,  epithelium ,  promoter (genetics) ,  *oral cavity ,  hyperplasia ,  *Telomerase ,  Cervical lymph node metastasis ,  *hTERT ,  membrane and film ,  histomembrane
Semi thesaurus term： 口腔癌 ,  上皮異形成 ,  口腔白斑 ,  口腔内扁平上皮癌 , 【Automatic Indexing@JST】

Author keywords (5)： Human telomerase reverse transcriptase ,  telomerase ,  DNA methylation ,  oral squamous cell carcinoma ,  oral leukoplakia

JST classification (1)： Gene expression  (EC02040Q)

Terms in the title (5)： ヒトテロメラーゼ逆転写酵素 ,  メチル化 ,  発現 ,  口腔 ,  発癌