Art

J-GLOBAL ID：201702277672426894   Reference number：17A0268450

Current status of primary pharmacotherapy and future perspectives toward upfront therapy for metastatic hormone-sensitive prostate cancer

転移ホルモン感受性前立腺癌に対する重要な治療に対する一次薬物療法の現状および最近の治療の将来の見通し

Author (2)： Shiota Masaki (Department of Urology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan) ,  Eto Masatoshi (Department of Urology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan)
Material： International Journal of Urology (Web)  (Int J Urol (Web))
Volume： 23  Issue： 5  Page： 360-369  Publication year： 2016 
JST Material Number： U0707A  ISSN： 1442-2042  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： *prostatic tumor ,...
Semi thesaurus term： *Carcinoma of the prostate metastatic ,...

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Author keywords (5)： abiraterone acetate ,  androgen deprivation therapy ,  enzalutamide ,  hormone-sensitive prostate cancer ,  taxane

JST classification (3)： Drug therapy(=pharmacotherapy)for tumors  (GE03032C) ,  Urogenital tumors(=neoplasms)  (GM04000S) ,  Clinical application of antitumor(=antineoplastic)drugs  (GW16020L)

Substance index (4)： Docetaxel ,  Cabazitaxel ,  abiraterone acetate ,  Enzalutamide

Reference (110)：

• Davison SL, Bell R. Androgen physiology. Semin. Reprod. Med. 2006; 24: 71-7.
• Montgomery RB, Mostaghel EA, Vessella R et al. Maintenance of intratumoral androgens in metastatic prostate cancer: a mechanism for castrationresistant tumor growth. Cancer Res. 2008; 68: 4447-54.
• Russell DW, Wilson JD. Steroid 5a-reductase: two genes/two enzymes. Annu. Rev. Biochem. 1994; 63: 25-61.
• Prescott J, Coetzee GA. Molecular chaperones throughout the life cycle of the androgen receptor. Cancer Lett. 2006; 231: 12-9.
• Shiota M, Yokomizo A, Fujimoto N, Naito S. Androgen receptor cofactors in prostate cancer: potential therapeutic targets of castration-resistant prostate cancer. Curr. Cancer Drug Targets 2011; 11: 870-81.

Terms in the title (6)： ホルモン感受性 ,  前立腺癌 ,  治療 ,  薬物療法 ,  現状 ,  見通し