Art

J-GLOBAL ID：201702278253651969   Reference number：17A0136562

CREB regulates TNF-α-induced GM-CSF secretion via p38 MAPK in human lung fibroblasts

CREBはヒト肺線維芽細胞においてp38MAPKを介してTNF-α誘導GM-CSF分泌を制御する

Author (13)： Koga Yasuhiko (Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine) ,  Hisada Takeshi (Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine) ,  Ishizuka Tamotsu (Third Department of Internal Medicine, Faculty of Medical Sciences, University of Fukui) ,  Utsugi Mitsuyoshi (Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine) ,  Utsugi Mitsuyoshi (Department of Respiratory Medicine, Kiryu Kosei General Hospital) ,  Ono Akihiro (Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine) ,  Yatomi Masakiyo (Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine) ,  Kamide Yosuke (Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine) ,  Kamide Yosuke (Clinical Research Center for Allergy and Rheumatology, Sagamihara National Hospital) ,  Aoki-Saito Haruka (Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine) ,  Tsurumaki Hiroaki (Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine) ,  Dobashi Kunio (Gunma University Graduate School of Health Sciences) ,  Yamada Masanobu (Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine)
Material： Allergology International  (Allergol Int)
Volume： 65  Issue： 4  Page： 406-413(J-STAGE)  Publication year： 2016 
JST Material Number： L6446A  ISSN： 1323-8930  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *GM-CSF ,...
Semi thesaurus term： *lung fibroblast ,...

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Author keywords (10)： Asthma ,  cAMP ,  CREB ,  GM-CSF ,  p38 MAPK ,  Asthma ,  cAMP ,  CREB ,  GM-CSF ,  p38 MAPK

JST classification (1)： Biological function  (EB03040U)

Reference (44)：

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• 4. Seminario MC, Gleich GJ. The role of eosinophils in the pathogenesis of asthma. Curr Opin Immunol 1994;6:860-4.
• 5. Takizawa H. Diesel exhaust particles and their effect on induced cytokine expression in human bronchial epithelial cells. Curr Opin Allergy Clin Immunol 2004;4:355-9.

Terms in the title (8)： CREB ,  ヒト ,  肺線維芽細胞 ,  p38MAPK ,  TNF-α ,  誘導 ,  GM-CSF ,  分泌