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J-GLOBAL ID：201702278348517845   Reference number：17A0791640

Long-term bioavailability of redox nanoparticles effectively reduces organ dysfunctions and death in whole-body irradiated mice

酸化還元ナノ粒子の長期バイオアベイラビリティは全身照射マウスにおける臓器機能不全と死を効果的に減少させる【Powered by NICT】

Author (8)： Feliciano Chitho P. (Department of Materials Science, Graduate School of Pure and Applied Sciences, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki, 305-8573, Japan) ,  Feliciano Chitho P. (Radiation Biology Research Group, Biomedical Research Section, Atomic Research Division, Philippine Nuclear Research Institute, Department of Science and Technology (PNRI-DOST), Commonwealth Avenue, Diliman, Quezon City, Philippines) ,  Tsuboi Koji (Proton Medical Research Center, University of Tsukuba, Japan) ,  Suzuki Kenshi (Proton Medical Research Center, University of Tsukuba, Japan) ,  Kimura Hiroyuki (Department of Analytical and Bioinorganic Chemistry, Kyoto Pharmaceutical University, Misasagi-Nakauchicho 5, Yamashinaku, Kyoto, Kyoto 607-8414, Japan) ,  Nagasaki Yukio (Department of Materials Science, Graduate School of Pure and Applied Sciences, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki, 305-8573, Japan) ,  Nagasaki Yukio (Master’s School of Medical Sciences, Graduate School of Comprehensive Human Sciences, Tennoudai 1-1-1, Tsukuba, Ibaraki, 305-8573, Japan) ,  Nagasaki Yukio (Satellite Laboratory, International Center of Materials Nanoarchitectonics (WPI-MANA), National Institute for Materials Science (NIMS), University of Tsukuba, Tennoudai 1-1-1, Tsukuba, Ibaraki, 305-8573, Japan)
Material： Biomaterials
Volume： 129  Page： 68-82  Publication year： 2017 
JST Material Number： C0964B  ISSN： 0142-9612  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： Radioprotective agents have be...

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Thesaurus term： biocompatibility ,  *whole body irradiation ,  covalent bond ,  ionizing radiation ,  *oxidation-reduction reaction ,  radiation protection ,  safety ,  lethal action ,  *nano particle ,  low molecular weight ,  radioactive ray ,  patient ,  *bioavailability ,  antioxidant ,  radioprotective drug

Author keywords (8)： Redox nanoparticles ,  Nitroxide radicals ,  Radiation protection ,  Radioprotector ,  Drug bioavailability ,  Whole-body irradiation ,  Ionizing radiation ,  Reactive oxygen species

JST classification (2)： Medical materials  (GA05040H) ,  Basic biopharmacy  (GY01021U)

Terms in the title (9)： 酸化還元 ,  ナノ粒子 ,  長期 ,  バイオアベイラビリティ ,  全身照射 ,  マウス ,  臓器 ,  機能不全 ,  死