Art

J-GLOBAL ID：201702278909068938   Reference number：17A1238620

ATP-binding cassette subfamily B member 1 1236C/T polymorphism significantly affects the therapeutic outcome of tacrolimus in patients with refractory ulcerative colitis

ATP結合カセットサブファミリーBメンバー11236C/T多型は難治性潰瘍性大腸炎患者におけるタクロリムスの治療転帰に有意に影響する【Powered by NICT】

Author (11)： Onodera Motoyuki (Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai, Japan) ,  Endo Katsuya (Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai, Japan) ,  Kakuta Yoichi (Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai, Japan) ,  Kuroha Masatake (Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai, Japan) ,  Kimura Tomoya (Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai, Japan) ,  Hiramoto Keiichiro (Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai, Japan) ,  Kanazawa Yoshitake (Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai, Japan) ,  Negoro Kenichi (Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai, Japan) ,  Shiga Hisashi (Department of Gastroenterology, Akita University Graduate School of Medicine, Akita, Japan) ,  Kinouchi Yoshitaka (Health Administration Center, Center for the Advancement of Higher Education, Tohoku University, Sendai, Japan) ,  Shimosegawa Tooru (Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai, Japan)
Material： Journal of Gastroenterology and Hepatology
Volume： 32  Issue： 9  Page： 1562-1569  Publication year： 2017 
JST Material Number： W2642A  ISSN： 0815-9319  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： BACKGROUND AND AIM: Tacrolimus...

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Thesaurus term： P glycoprotein ,  remission ,  metabolism ,  genetic polymorphism ,  *therapy ,  *patient ,  *ulcerative colitis ,  genotype ,  ether ,  ketone ,  macrocyclic compound ,  nitrogen heterocyclic compound ,  oxygen heterocyclic compound ,  bridged compound ,  allyl compound ,  alicyclic alcohol
Semi thesaurus term： 多変量ロジスティック回帰分析 ,  遺伝子タイピング ,  日本人 ,  臨床効果 ,  *転帰 ,  *ATP結合カセット , 【Automatic Indexing@JST】

Author keywords (4)： ABCB1 ,  CYP ,  tacrolimus ,  ulcerative colitis

JST classification (2)： Drug therapy(=pharmacotherapy)for digestive system diseases  (GH05020G) ,  Treatment for digestive system diseases in general  (GH05010V)

Substance index (1)： Tacrolimus

Terms in the title (10)： ATP結合カセット ,  サブ ,  ファミリー ,  メンバー ,  多型 ,  難治性潰瘍性大腸炎 ,  患者 ,  タクロリムス ,  治療 ,  転帰