Art

J-GLOBAL ID：201702280257048664   Reference number：17A0854726

Elevated serum MFG-E8 level is possibly associated with the presence of high-intensity cerebral lesions on magnetic resonance imaging in patients with systemic lupus erythematosus

血清MFG-E8量の増加は全身性エリテマトーデス患者において磁気共鳴造影での高強度脳病変の存在と関係する可能性がある

Author (3)： Kishi Chikako (Department of Dermatology, Gunma University Graduate School of Medicine, Maebashi, Japan) ,  Motegi Sei-ichiro (Department of Dermatology, Gunma University Graduate School of Medicine, Maebashi, Japan) ,  Ishikawa Osamu (Department of Dermatology, Gunma University Graduate School of Medicine, Maebashi, Japan)
Material： Journal of Dermatology  (J Dermatol)
Volume： 44  Issue： 7  Page： 783-788  Publication year： Jul. 2017 
JST Material Number： W1578A  ISSN： 0385-2407  Document type： Article
Article type： 原著論文  Country of issue： Australia (AUS)  Language： ENGLISH (EN)

Thesaurus term： glycoprotein ,...
Semi thesaurus term： activity of disease ,...

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Author keywords (5)： cerebrovascular disease ,  MFG-E8 ,  neuropsychiatric systemic lupus erythematosus ,  systemic lupus erythematosus ,  Systemic Lupus Erythematosus Disease Activity Index

JST classification (4)： Diagnostics of immunologic diseases,allergic diseases.  (GD04020N) ,  Neurologic diagnosis  (GN02000H) ,  Cardiovascular system diagnosis  (GJ02000V) ,  Biological function  (EB03040U)

Reference (29)：

• D'Cruz DP, Khamashta MA, Hughes GR. Systemic lupus erythematosus. Lancet 2007; 369: 587-596.
• Gaipl US, Voll RE, Sheriff A, Franz S, Kalden JR, Herrmann M. Impaired clearance of dying cells in systemic lupus erythematosus. Autoimmun Rev 2005; 4: 189-194.
• Ogura K, Nara K, Watanabe Y, Kohno K, Tai T, Sanai Y. Cloning and expression of cDNA for O-acetylation of GD3 ganglioside. Biochem Biophys Res Commun 1993; 225: 932-938.
• Raymond A, Ensslin MA, Shur BD. SED1/MFG-E8: a bi-motif protein that orchestrates diverse cellular interactions. J Cell Biochem 2009; 106: 957-966.
• Motegi S, Leitner WW, Lu M et al. Pericyte-derived MFG-E8 regulates pathologic angiogenesis. Arterioscler Thromb Vasc Biol 2011a; 31: 2024-2034.

Terms in the title (9)： 血清 ,  MFG-E8 ,  全身性エリテマトーデス ,  患者 ,  磁気共鳴 ,  造影 ,  高強度 ,  脳病変 ,  可能性