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J-GLOBAL ID：201702280923957705   Reference number：17A1973917

Generation of a Motor Nerve Organoid with Human Stem Cell-Derived Neurons

ヒト幹細胞由来ニューロンを用いた運動神経類器官の発生【Powered by NICT】

Author (12)： Kawada Jiro (Institute of Industrial Science, The University of Tokyo, Tokyo 153-8505, Japan) ,  Kaneda Shohei (Institute of Industrial Science, The University of Tokyo, Tokyo 153-8505, Japan) ,  Kirihara Takaaki (Institute of Industrial Science, The University of Tokyo, Tokyo 153-8505, Japan) ,  Kirihara Takaaki (Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, Tokyo 113-8656, Japan) ,  Maroof Asif (Department of Stem Cell and Regenerative Biology, and Harvard Stem Cell Institute, Harvard University, Cambridge, MA 02138, USA) ,  Maroof Asif (Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA) ,  Levi Timothee (Institute of Industrial Science, The University of Tokyo, Tokyo 153-8505, Japan) ,  Eggan Kevin (Department of Stem Cell and Regenerative Biology, and Harvard Stem Cell Institute, Harvard University, Cambridge, MA 02138, USA) ,  Eggan Kevin (Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA) ,  Fujii Teruo (Institute of Industrial Science, The University of Tokyo, Tokyo 153-8505, Japan) ,  Ikeuchi Yoshiho (Institute of Industrial Science, The University of Tokyo, Tokyo 153-8505, Japan) ,  Ikeuchi Yoshiho (Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, Tokyo 113-8656, Japan)
Material： Stem Cell Reports
Volume： 9  Issue： 5  Page： 1441-1449  Publication year： 2017 
JST Material Number： W3132A  ISSN： 2213-6711  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： During development, axons spon...

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Thesaurus term： channel ,  axon ,  *neuron ,  robustness ,  elasticity (mechanical property) ,  *human ,  in vitro experiment ,  *stem cell ,  spheroid ,  *motor nerve ,  microenvironment ,  *Nerve ,  *organ ,  mechanical property
Semi thesaurus term： 薬物スクリーニング ,  マイクロデバイス , 【Automatic Indexing@JST】

Author keywords (5)： motor nerve ,  iPS cells ,  axon ,  fascicle ,  organoid

JST classification (2)： Nervous system in general  (EJ12010J) ,  Central nervous system  (EJ12030F)

Terms in the title (5)： ヒト ,  幹細胞 ,  ニューロン ,  運動神経 ,  器官