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J-GLOBAL ID：201702281139966706   Reference number：17A0316818

Antagonists to endothelin receptor type B promote apoptosis in human pulmonary arterial smooth muscle cells

エンドセリン受容体B型へのきっ抗薬はヒト肺動脈平滑筋細胞におけるアポトーシスを促進する【Powered by NICT】

Author (8)： Sakai Satoshi (Division of Cardiovascular Medicine, Department of Clinical Medicine, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan) ,  Maruyama Hidekazu (Division of Cardiovascular Medicine, Department of Clinical Medicine, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan) ,  Kimura Taizo (Division of Cardiovascular Medicine, Department of Clinical Medicine, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan) ,  Tajiri Kazuko (Division of Cardiovascular Medicine, Department of Clinical Medicine, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan) ,  Honda Junya (Division of Cardiovascular Medicine, Department of Clinical Medicine, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan) ,  Homma Satoshi (Division of Cardiovascular Medicine, Department of Clinical Medicine, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan) ,  Aonuma Kazutaka (Division of Cardiovascular Medicine, Department of Clinical Medicine, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan) ,  Miyauchi Takashi (Division of Cardiovascular Medicine, Department of Clinical Medicine, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan)
Material： Life Sciences  (Life Sciences including Pharmacology Letters)
Volume： 159  Page： 116-120  Publication year： 2016 
JST Material Number： B0699B  ISSN： 0024-3205  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Vascular remodeling results fr...

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Thesaurus term： *endothelin ,  *apoptosis ,  antineoplastic antibiotics ,  vascular smooth muscle cell ,  vascular remodeling ,  caspase ,  *human(primates) ,  *receptor ,  cell proliferation ,  Western blotting ,  p53 protein ,  cell death ,  cyclopeptide ,  oligopeptide
Semi thesaurus term： *アンタゴニスト , 【Automatic Indexing@JST】

Author keywords (4)： Endothelin receptor antagonist ,  Apoptosis ,  Pulmonary arterial smooth muscle cell ,  Pulmonary vascular remodeling

JST classification (2)： Bioactive peptides  (EB08100U) ,  Basic medicine on cardiovascular system  (GJ01020K)

Substance index (2)： BQ-123 ,  BQ-788

Terms in the title (6)： エンドセリン受容体 ,  きっ抗薬 ,  ヒト ,  肺動脈平滑筋細胞 ,  アポトーシス ,  促進