Art

J-GLOBAL ID：201702281982116207   Reference number：17A0760585

First total synthesis of glabramycin B and revision of its relative configuration

グラブラマイシンBの初めての全合成とその相対配置の修正

Author (3)： Yamamoto Masaoki (Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo, 113-8657, Japan) ,  Ishigami Ken (Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo, 113-8657, Japan) ,  Watanabe Hidenori (Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo, 113-8657, Japan)
Material： Tetrahedron  (Tetrahedron Symposia-in-Print)
Volume： 73  Issue： 23  Page： 3271-3280  Publication year： Jun. 08, 2017 
JST Material Number： E0234A  ISSN： 0040-4020  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： *total synthesis ,  *asymmetric synthesis ,  antibiotics ,  cross coupling reaction ,  alkylation ,  steric configuration ,  correction(modification) ,  natural material ,  *lactone ,  macrocyclic compound ,  *unsaturated carboxylic acid
Semi thesaurus term： Stille coupling reaction ,  *Macrolides ,  *relative configuration

Author keywords (5)： Glabramycin B ,  Ten-membered lactone ,  Antibiotics ,  Determination of the relative configuration ,  Sch 642305

JST classification (2)： Eight or more-membered heterocyclic compounds  (CF07120T) ,  Aliphatic carboxylic acids,peroxycarboxylic acids,thiocarboxylic acids  (CF03200E)

Substance index (1)： (2E,4E,6E)-7-[(1S,6S,11R,11aS)-1,6,7,8,9,10,11,11a-Octahydro-6-methyl-4,12-dioxo-1,11-propano-4H-2,5-dioxa-2H-cyclopentacyclodecene-3-yl]-2,4,6-heptatrienoic acid

Terms in the title (4)： グラブ ,  ラマイシン ,  全合成 ,  相対配置