Art

J-GLOBAL ID：201702282856855405   Reference number：17A0441702

Application of Terahertz Attenuated Total Reflection Spectroscopy to Detect Changes in the Physical Properties of Lactose during the Lubrication Process Required for Drug Formulation

製剤に必要な滑沢過程中の乳糖の物理的特性における変化を検出するための全反射減衰テラヘルツ分光法の適用

Author (8)： Dohi Masafumi (Pharmaceutical Research & Technology Laboratories, Astellas Pharma Inc.) ,  Dohi Masafumi (Faculty of Pharmaceutical Science, Toho University) ,  Momose Wataru (Pharmaceutical Research & Technology Laboratories, Astellas Pharma Inc.) ,  Yamashita Kazunari (Pharmaceutical Research & Technology Laboratories, Astellas Pharma Inc.) ,  Hakomori Tadashi (Pharmaceutical Research & Technology Laboratories, Astellas Pharma Inc.) ,  Sato Shusaku (Advantest Corporation) ,  Noguchi Shuji (Faculty of Pharmaceutical Science, Toho University) ,  Terada Katsuhide (Faculty of Pharmaceutical Science, Toho University)
Material： Chemical and Pharmaceutical Bulletin  (Chemical & Pharmaceutical Bulletin)
Volume： 65  Issue： 2  Page： 186-193(J-STAGE)  Publication year： 2017 
JST Material Number： G0504A  ISSN： 0009-2363  CODEN： CPBTAL  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *tablet (pharmaceuticals) ,...
Semi thesaurus term： *attenuated total reflection

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Author keywords (12)： terahertz pulsed spectroscopy ,  attenuated total reflection ,  lubrication ,  lactose ,  magnesium stearate ,  evanescent wave ,  terahertz pulsed spectroscopy ,  attenuated total reflection ,  lubrication ,  lactose ,  magnesium stearate ,  evanescent wave

JST classification (1)： Solid preparations  (GY02030V)

Substance index (2)： Lactose ,  Magnesium stearate

Reference (35)：

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• 3) Bolhuis G. K., De Jong S. W., Lerk C. F., Dettmers H., Pharbita B. V., Drug Dev. Ind. Pharm., 13, 1547-1567 (1987).
• 4) Kushner J. 4th, Moore F., Int. J. Pharm., 399, 19-30 (2010).
• 5) Kushner J. 4th, Int. J. Pharm., 429, 1-11 (2012).

Terms in the title (7)： 製剤 ,  滑 ,  過程 ,  乳糖 ,  物理的特性 ,  全反射減衰 ,  テラヘルツ分光法