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J-GLOBAL ID：201702282864034661   Reference number：17A1116200

Inhibition of epithelial-mesenchymal transition by cetuximab via the EGFR-GEP100-Arf6-AMAP1 pathway in head and neck cancer

頭頸部癌におけるEGFR GEP100Arf6AMAP1経路を介してセツキシマブによる上皮間葉転換の阻害【Powered by NICT】

Author (9)： Matsumoto Yoshifumi (Department of Otolaryngology, Head and Neck Surgery, Kyorin University School of Medicine, Tokyo, Japan) ,  Sakurai Hiroyuki (Departments of Pharmacology and Toxicology, Kyorin University School of Medicine, Tokyo, Japan) ,  Kogashiwa Yasunao (Department of Head and Neck Surgery and Otolaryngology, Saitama Medical University International Medical Center, Hidaka, Saitama, Japan) ,  Kimura Toru (Departments of Pharmacology and Toxicology, Kyorin University School of Medicine, Tokyo, Japan) ,  Matsumoto Yuma (Department of Otolaryngology, Head and Neck Surgery, Kyorin University School of Medicine, Tokyo, Japan) ,  Shionome Takashi (Department of Partial Denture Prosthodontics, Nihon University School of Dentistry, Kanda, Chiyoda-ku, Tokyo, Japan) ,  Asano Masatake (Department of Pathology, Nihon University School of Dentistry, Tokyo, Japan, Kanda, Chiyoda-ku, Tokyo, Japan) ,  Saito Koichiro (Department of Otolaryngology, Head and Neck Surgery, Kyorin University School of Medicine, Tokyo, Japan) ,  Kohno Naoyuki (Department of Otolaryngology, Head and Neck Surgery, Kyorin University School of Medicine, Tokyo, Japan)
Material： Head & Neck: Journal for the Sciences & Specialties of the Head and Neck
Volume： 39  Issue： 3  Page： 476-485  Publication year： 2017 
JST Material Number： W2592A  ISSN： 1043-3074  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： BACKGROUND: Despite improved s...

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Thesaurus term： growth factor ,  drug therapy ,  *head and neck tumor ,  immersional wetting ,  monoclonal antibody ,  radiotherapy ,  *EGF receptor ,  tumor cell ,  *epithelium ,  survival ratio ,  heterotrans plantation ,  squamous cell carcinoma
Semi thesaurus term： *GEP100 ,  *上皮間葉転換 ,  *セツキシマブ , 【Automatic Indexing@JST】

Author keywords (5)： cetuximab ,  GEP100 ,  AMAP1 ,  epithelial-mesenchymal transition ,  head and neck

JST classification (2)： Drug therapy(=pharmacotherapy)for tumors  (GE03032C) ,  Tumors(=neoplasms)of digestive system  (GH04000D)

Terms in the title (6)： 頭頸部癌 ,  EGFR ,  経路 ,  セツキシマブ ,  上皮間葉転換 ,  阻害