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J-GLOBAL ID：201702284336587277   Reference number：17A1459633

Structural studies of amyloid-β peptides: Unlocking the mechanism of aggregation and the associated toxicity

アミロイドβペプチドの構造研究:凝集および付随した毒性の解除機構【Powered by NICT】

Author (8)： Aleksis Rihards (Department of Physical Organic Chemistry, Latvian Institute of Organic Synthesis, Aizkraukles 21, Riga, Latvia) ,  Oleskovs Filips (Department of Physical Organic Chemistry, Latvian Institute of Organic Synthesis, Aizkraukles 21, Riga, Latvia) ,  Jaudzems Kristaps (Department of Physical Organic Chemistry, Latvian Institute of Organic Synthesis, Aizkraukles 21, Riga, Latvia) ,  Pahnke Jens (Department of Neuro-/Pathology, Translational Neurodegeneration Research and Neuropathology Lab, University of Oslo (UiO) & Oslo University Hospital (OUS), Norway) ,  Pahnke Jens (LIED, University of Luebeck Uzl, Germany) ,  Pahnke Jens (Leibniz-Institute of Plant Biochemistry (IPB), Halle, Germany) ,  Biverstal Henrik (Department of Physical Organic Chemistry, Latvian Institute of Organic Synthesis, Aizkraukles 21, Riga, Latvia) ,  Biverstal Henrik (Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Karolinska Institutet, Stockholm, Sweden)
Material： Biochimie
Volume： 140  Page： 176-192  Publication year： 2017 
JST Material Number： B0147A  ISSN： 0300-9084  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Alzheimer’s disease (AD) is on...

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Thesaurus term： *toxicity ,  instability ,  *peptide ,  neurotoxicity ,  Alzheimer Disease ,  solid phase ,  amyloid plaque ,  Pathology ,  NMR ,  *aggregation ,  *Amyloid ,  aggregate ,  Neurodegenerative Diseases ,  phase (thermodynamics) ,  *Proteins ,  *glycoprotein ,  *animal protein
Semi thesaurus term： 発症 ,  *アミロイドβペプチド , 【Automatic Indexing@JST】

Author keywords (5)： Alzheimer’s disease ,  Amyloid-β peptide ,  Amyloid structure ,  Aggregation mechanism ,  Neurotoxicity

JST classification (2)： Basic neurology  (GN01020W) ,  Biological function  (EB03040U)

Terms in the title (4)： アミロイドβペプチド ,  研究 ,  凝集 ,  毒性