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J-GLOBAL ID：201702286528002596   Reference number：17A1428397

1α,25-Dihydroxyvitamin D₃ enhances TRPV6 transcription through p38 MAPK activation and GADD45 expression

1α,25-ジヒドロキシビタミンD_3はp38MAPK活性化とGADD45発現を介してTRPV6転写を増強する【Powered by NICT】

Author (6)： Ishizawa Michiyasu (Division of Biochemistry, Department of Biomedical Sciences, Nihon University School of Medicine, 30-1 Oyaguchi-kamicho, Itabashi-ku, Tokyo 173-8610, Japan) ,  Akagi Daisuke (Division of Biochemistry, Department of Biomedical Sciences, Nihon University School of Medicine, 30-1 Oyaguchi-kamicho, Itabashi-ku, Tokyo 173-8610, Japan) ,  Akagi Daisuke (Department of Applied Biological Science, Nihon University College of Bioresource Sciences, Fujisawa, Kanagawa 252-8510, Japan) ,  Yamamoto Jumpei (Division of Biochemistry, Department of Biomedical Sciences, Nihon University School of Medicine, 30-1 Oyaguchi-kamicho, Itabashi-ku, Tokyo 173-8610, Japan) ,  Yamamoto Jumpei (Department of Applied Biological Science, Nihon University College of Bioresource Sciences, Fujisawa, Kanagawa 252-8510, Japan) ,  Makishima Makoto (Division of Biochemistry, Department of Biomedical Sciences, Nihon University School of Medicine, 30-1 Oyaguchi-kamicho, Itabashi-ku, Tokyo 173-8610, Japan)
Material： Journal of Steroid Biochemistry & Molecular Biology  (Journal of Steroid Biochemistry and Molecular Biology)
Volume： 172  Page： 55-61  Publication year： 2017 
JST Material Number： C0595A  ISSN： 0960-0760  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： The active form of vitamin D, ...

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Thesaurus term： hypercalcemia ,  inactivation ,  *vitamin D ,  bone metabolism ,  *p38 MAP kinase ,  vitamin D receptor ,  cell proliferation
Semi thesaurus term： キナーゼ ,  阻害剤 ,  *P38 ,  標的遺伝子 ,  SW480細胞 ,  リガンド ,  *TRPV6 ,  *GADD45 , 【Automatic Indexing@JST】

Author keywords (6)： Vitamin D receptor ,  TRPV6 ,  CYP24A1 ,  p38 MAP kinase ,  GADD45 ,  Transcription

JST classification (1)： Vitamin D  (EB07050H)

Terms in the title (7)： p38MAPK ,  活性化 ,  GADD45 ,  発現 ,  TRPV6 ,  転写 ,  増強