Art

J-GLOBAL ID：201702287488629129   Reference number：17A1907603

Successful tocilizumab therapy in seven patients with refractory adult-onset Still’s disease

難治性成人発症Still病の7名の患者における成功裏のトシリズマブ療法

Author (10)： BANNAI Ei (National Center for Global Health and Medicine, Tokyo, JPN) ,  YAMASHITA Hiroyuki (National Center for Global Health and Medicine, Tokyo, JPN) ,  KANEKO Shunta (National Center for Global Health and Medicine, Tokyo, JPN) ,  UEDA Yo (National Center for Global Health and Medicine, Tokyo, JPN) ,  OZAKI Takashi (National Center for Global Health and Medicine, Tokyo, JPN) ,  TSUCHIYA Haruka (National Center for Global Health and Medicine, Tokyo, JPN) ,  TAKAHASHI Yuko (National Center for Global Health and Medicine, Tokyo, JPN) ,  KANEKO Hiroshi (National Center for Global Health and Medicine, Tokyo, JPN) ,  KANO Toshikazu (National Center for Global Health and Medicine, Tokyo, JPN) ,  MIMORI Akio (National Center for Global Health and Medicine, Tokyo, JPN)
Material： Modern Rheumatology  (Mod Rheumatol)
Volume： 26  Issue： 2  Page： 297-301  Publication year： Mar. 2016 
JST Material Number： L5142A  ISSN： 1439-7595  Document type： Article
Article type： 短報  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： *rheumatoid arthritis ,...
Semi thesaurus term： *Adult onset still's disease ,...

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JST classification (3)： Treatment for immunologic diseases,allergic diseases.  (GD04030Y) ,  Clinical application of anti-inflammatory drugs  (GW15020E) ,  Drug therapy(=pharmacotherapy)for musculoskeletal diseases  (GG05020D)

Substance index (2)： Prednisolone ,  Ciclosporin

Reference (27)：

• Efthimiou P, Paik PK, Bielory L. Diagnosis and management of adult onset Still's disease. Ann Rheum Dis. 2006;65(5):564-72.
• Ohta A, Yamaguchi M, Tsunematsu T, Kasukawa R, Mizushima H, Kashiwagi H, et al. Adult Still's disease: a multicenter survey of Japanese patients. J Rheumatol. 1990;17(8):1058-63.
• Aydintug AO, D’Cruz D, Cervera R, Khamashta MA, Hughes GR. Low dose methotrexate treatment in adult Still's disease. J Rheumatol. 1992;19(3):431-5.
• Scheinberg MA, Chapira E, Fernandes ML, Hubscher O. Interleukin 6: a possible marker of disease activity in adult onset Still's disease. Clin Exp Rheumatol. 1996;14(6):653-5.
• Efthimiou P, Kontzias A, Ward CM, Ogden NS. Adult-onset Still's disease: can recent advances in our understanding of its pathogenesis lead to targeted therapy?Nat Clin Pract Rheumatol. 2007;3(6):328-35.

Terms in the title (4)： 成人発症Still病 ,  患者 ,  トシリズマブ ,  療法