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J-GLOBAL ID：201702287632126933   Reference number：17A0506662

Activation of G protein-coupled estrogen receptor 1 mimics, but does not mediate, the anti-proliferative action of estradiol on pituitary lactotrophs in primary culture

Gタンパク質共役型エストロゲン受容体1の活性化は初代培養での下垂体乳腺刺激ホルモン分泌細胞に対するエストラジオールの候増殖作用を模倣するがこれを仲介しない

Author (4)： Mitsui Tetsuo (Department of Physiology, Graduate School of Medicine, University of Yamanashi, Yamanashi 409-3898, Japan) ,  Ishida Maho (Department of Physiology, Graduate School of Medicine, University of Yamanashi, Yamanashi 409-3898, Japan) ,  Izawa Michi (Department of Physiology, Graduate School of Medicine, University of Yamanashi, Yamanashi 409-3898, Japan) ,  Arita Jun (Department of Physiology, Graduate School of Medicine, University of Yamanashi, Yamanashi 409-3898, Japan)
Material： Endocrine Journal  (Endocr J)
Volume： 64  Issue： 1  Page： 103-115(J-STAGE)  Publication year： 2017 
JST Material Number： F0625A  ISSN： 0918-8959  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *estrogen receptor ,...
Semi thesaurus term： G protein-coupled receptor ,...

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Author keywords (5)： Estrogen ,  G protein-coupled estrogen receptor 1 ,  Estrogen receptor ,  Lactotroph ,  Proliferation

JST classification (1)： Basic medicine on endocrine system  (GL01020Q)

Substance index (2)： Estradiol ,  Diethylstilbestrol

Reference (47)：

• 1. Deroo BJ, Korach KS (2006) Estrogen receptors and human disease. J Clin Invest 116: 561-570.
• 2. Jordan VC, O’Malley BW (2007) Selective estrogen-receptor modulators and antihormonal resistance in breast cancer. J Clin Oncol 25: 5815-5824.
• 3. Sullivan TR Jr, Karas RH, Aronovitz M, Faller GT, Ziar JP, et al. (1995) Estrogen inhibits the response-to-injury in a mouse carotid artery model. J Clin Invest 96: 2482-2488.
• 4. Uchima FDA, Edery M, Iguchi T, Bern HA (1991) Growth of mouse endometrial luminal epithelial cells in vitro: functional integrity of the oestrogen receptor system and failure of oestrogen to induce proliferation. J Endocrinol 128: 115-120.
• 5. Huggins C, Yang NC (1962) Induction and extinction of mammary cancer. A striking effect of hydrocarbons permits analysis of mechanisms of causes and cure of breast cancer. Science 137: 257-262.

Terms in the title (11)： Gタンパク質 ,  共役 ,  エストロゲン受容体1 ,  活性化 ,  初代培養 ,  下垂体 ,  乳腺刺激ホルモン分泌細胞 ,  エストラジオール ,  増殖 ,  模倣 ,  仲介