Art

J-GLOBAL ID：201702288661781474   Reference number：17A1301182

Evolutionary well-conserved region in the signal peptide of parathyroid hormone-related protein is critical for its dual localization through the regulation of ER translocation

副甲状腺ホルモン関連蛋白質のシグナルペプチドにおいて進化的に良く保存された領域は,小胞体移行の調節を通してそれの二重局在性に決定的である

Author (3)： AMAYA Yoshihiro (Niigata Univ. Graduate School of Medical and Dental Sci., Niigata, JPN) ,  NAKAI Toshiki (Yokohama City Univ. School of Medicine, Yokohama, JPN) ,  MIURA Satoshi (Yokohama City Univ. School of Medicine, Yokohama, JPN)
Material： Journal of Biochemistry  (JB)
Volume： 159  Issue： 4  Page： 393-406  Publication year： Apr. 2016 
JST Material Number： W1920A  ISSN： 0021-924X  CODEN： JOBIAO  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： *PTHRP ,...
Semi thesaurus term： N-terminal residue ,...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=17A1301182&from=J-GLOBAL&jstjournalNo=W1920A") }}

JST classification (3)： Biological function  (EB03040U) ,  Cell physiology in general  (EF02010S) ,  Animal biochemistry  (EJ01050P)

Reference (31)：

• Wysolmerski, J.J. and Stewart, A.F. (1998) The physiology of parathyroid hormone-related protein: an emerging roles as a developmental factor. Annu. Rev. Physiol. 60, 431-460
• Henderson, J.E., Amizuka, N., Warshawsky, H., Biasotto, D., Lanske, B.M.K., Goltzman, D., and Karaplis, A.C. (1995) Nucleolar localization of parathyroid hormone-related peptide enhances survival of chondrocytes under conditions that promote apototic cell death. Mol. Cell Biol. 15, 4064-4075
• Fiaschi-Taesch, N.M. and Stewart, A.F. (2003) Parathyroid hormone-related protein as an intracrine factor-trafficking mechanisms and functional consequences. Endocrinology 144, 407-411
• Aarts, M.M., Rix, A., Guo, J., Bringhurst, R., and Henderson, J.E. (1999) The nucleolar targeting signal (NTS) of parathyroid hormone related protein mediates endocytosis and nucleolar translocation. J. Bone Miner. Res. 14, 1493-1503
• Nguyen, M.T.A., He, B., and Karaplis, A.C. (2001) Nuclear forms of parathyroid hormone-related peptide are translated from non-AUG start sites downstream from the initiator methionine. Endocrynology 142, 694-703

Terms in the title (8)： 副甲状腺ホルモン関連蛋白質 ,  シグナルペプチド ,  進化 ,  保存 ,  小胞体 ,  移行 ,  調節 ,  局在性