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J-GLOBAL ID：201702288997568767   Reference number：17A1159215

Up-Regulation of Transient Receptor Potential Melastatin 6 Channel Expression by Tumor Necrosis Factor-α in the Presence of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor

上皮成長因子受容体チロシンキナーゼ阻害剤の存在下での腫瘍壊死因子-αによる一過性受容体電位メラスタチン6チャンネル発現のアップレギュレーション【Powered by NICT】

Author (10)： Furukawa Chisa (Laboratory of Biochemistry, Department of Biopharmaceutical Sciences, Gifu Pharmaceutical University, Gifu, Japan) ,  Fujii Naoko (Laboratory of Biochemistry, Department of Biopharmaceutical Sciences, Gifu Pharmaceutical University, Gifu, Japan) ,  Manabe Aya (Laboratory of Biochemistry, Department of Biopharmaceutical Sciences, Gifu Pharmaceutical University, Gifu, Japan) ,  Matsunaga Toshiyuki (Laboratory of Biochemistry, Department of Biopharmaceutical Sciences, Gifu Pharmaceutical University, Gifu, Japan) ,  Endo Satoshi (Laboratory of Biochemistry, Department of Biopharmaceutical Sciences, Gifu Pharmaceutical University, Gifu, Japan) ,  Hasegawa Hajime (Saitama Medical Center, Saitama Medical University, Saitama, Japan) ,  Ito Yoshinori (Department of Pharmacy, Gifu University Hospital, Gifu, Japan) ,  Yamaguchi Masahiko (School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan) ,  Yamazaki Yasuhiro (School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan) ,  Ikari Akira (Laboratory of Biochemistry, Department of Biopharmaceutical Sciences, Gifu Pharmaceutical University, Gifu, Japan)
Material： Journal of Cellular Physiology  (J Cell Physiol)
Volume： 232  Issue： 10  Page： 2841-2850  Publication year： 2017 
JST Material Number： E0042B  ISSN： 0021-9541  CODEN： JCLLA  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： Anti-epidermal growth factor r...

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Thesaurus term： NF-kappaB ,  EGF ,  *EGF receptor ,  binding site ,  ERK ,  kidney tubule ,  *Up-Regulation ,  human ,  TNF alpha ,  *epithelium ,  phosphorylation ,  Erk1/2 ,  TRPM6 ,  *membrane and film ,  *histomembrane ,  enzyme inhibitor
Semi thesaurus term： *阻害剤 , 【Automatic Indexing@JST】

JST classification (2)： Gene expression  (EC02040Q) ,  Cell physiology in general  (EF02010S)

Substance index (1)： Erlotinib

Terms in the title (7)： 上皮成長因子受容体チロシンキナーゼ阻害剤 ,  腫瘍壊死因子 ,  受容体 ,  電位 ,  チャンネル ,  発現 ,  アップレギュレーション